SCHEMBL2335378

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Hydrochloric Acid SCHEMBL3302265	0.99	DRD4 (0.56)	DRD4HTR4FAAHACHELMNA
	SCHEMBL2334767	0.90	HTR4 (0.60)	DRD4HTR4
	SCHEMBL2335431	0.90	HTR4 (0.58)	DRD4HTR4FAAHACHEALDH1A1
	SCHEMBL2340631	0.89	HTR4 (0.57)	DRD4HTR4FAAHACHE
	SCHEMBL2336956	0.89	HTR4 (0.57)	DRD4HTR4
	Hydrochloric Acid SCHEMBL3299088	0.89	HTR4 (0.57)	DRD4HTR4FAAHACHEALDH1A1
	SCHEMBL3299419	0.88	HTR4 (0.55)	DRD4HTR4ALDH1A1MAPT
	Hydrochloric Acid SCHEMBL3333373	0.84	HTR4 (0.53)	DRD4HTR4
	SCHEMBL2337607	0.83	HTR4 (0.58)	HTR4LMNAALDH1A1
	SCHEMBL15103539	0.82	HTR4 (0.52)	DRD4HTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.