SCHEMBL233541

SCHEMBL233541

CNC(CCc1ncc(C[C@H](N)C(=O)O)[nH]1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.43
CYP3A4 P08684 1/20 0.43
HTR1B P28222 2/20 0.39
MTOR P42345 1/20 0.39
SLC1A3 P43003 1/20 0.37
GRIA1 P42261 1/20 0.35
GRIA2 P42262 1/20 0.35
GRIA3 P42263 1/20 0.35
GRIA4 P48058 1/20 0.35
HRH1 P35367 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ALPI P09923 1/20 0.33
PKM P14618 1/20 0.33
PTGS1 P23219 1/20 0.33
XIAP P98170 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL849758 0.84 SLC7A5 (0.51) SLC7A5CYP3A4HTR1BSLC1A3GRIA1
SCHEMBL29022740 0.82 SLC7A5 (0.47) SLC7A5CYP3A4HTR1BMTORSLC1A3
SCHEMBL29637251 0.79 SLC7A5 (0.43) SLC7A5CYP3A4HTR1BMTORSLC1A3
SCHEMBL29356218 0.79 SLC7A5 (0.51) SLC7A5CYP3A4SLC1A3GRIA1GRIA2
SCHEMBL4453505 0.79 SLC7A5 (0.41) SLC7A5CYP3A4HTR1BMTORSLC1A3
SCHEMBL8319666 0.78 CYP3A4 (0.48) SLC7A5CYP3A4SLC1A3GRIA1GRIA2
SCHEMBL233540 0.77 SLC7A5 (0.39) SLC7A5CYP3A4MTORGRIA1GRIA2
SCHEMBL29022786 0.77 SLC7A5 (0.39) SLC7A5CYP3A4MTORGRIA1GRIA2
SCHEMBL27446953 0.76 SLC7A5 (0.51) SLC7A5CYP3A4SLC1A3GRIA1GRIA2
Methylamine SCHEMBL29022748 0.76 CYP3A4 (0.46) SLC7A5CYP3A4SLC1A3GRIA1GRIA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116298235-A Serum metabolism biomarker for diagnosing or monitoring breast cancer and screening method thereof 哈尔滨医科大学 2023-06-23 CN claimed
CN-116298235-A Serum metabolism biomarker for diagnosing or monitoring breast cancer and screening method thereof 哈尔滨医科大学 2023-06-23 CN disclosed
EP-2463654-B1 Compositions and methods for modeling saccharomyces cerevisiae metabolism UNIV CALIFORNIA (US) 2020-06-03 EP disclosed
EP-2279417-B1 METABOLIC BIOMARKERS FOR OVARIAN CANCER AND METHODS OF USE THEREOF GEORGIA TECH RES INST (US) 2016-07-20 EP disclosed
EP-2463654-A1 Compositions and methods for modeling saccharomyces cerevisiae metabolism The Regents of The University of California (US) 2012-06-13 EP disclosed
US-8170852-B2 Data structures and methods for modeling Saccharomyces cerevisiae metabolism THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-05-01 US disclosed
EP-2434421-A2 Compositions and methods for modeling saccharomyces cerevisiae metabolism The Regents of The University of California (US) 2012-03-28 EP disclosed
US-20120004854-A1 METABOLIC BIOMARKERS FOR OVARIAN CANCER AND METHODS OF USE THEREOF GEORGIA TECH RESEARCH CORPORATION 2012-01-05 US disclosed
EP-2279417-A1 METABOLIC BIOMARKERS FOR OVARIAN CANCER AND METHODS OF USE THEREOF Georgia Tech Research Corporation (US) 2011-02-02 EP disclosed
US-20100280803-A1 Compositions and Methods for Modeling Saccharomyces cerevisiae Metabolism THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2010-11-04 US disclosed
EP-2230312-A1 Probe compound for detecting and isolating enzymes and means and methods using the same Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2010-09-22 EP disclosed
US-7751981-B2 Articles of manufacture and methods for modeling Saccharomyces cerevisiae metabolism THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-07-06 US disclosed
WO-2009151967-A1 METABOLIC BIOMARKERS FOR OVARIAN CANCER AND METHODS OF USE THEREOF GEORGIA TECH RESEARCH CORPORATION (US) 2009-12-17 WO disclosed