Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29022740 | 0.88 | SLC7A5 (0.47) | SLC7A5CYP3A4SLC1A3GRIA1GRIA2 | |
| SCHEMBL29356218 | 0.87 | SLC7A5 (0.51) | SLC7A5CYP3A4SLC1A3GRIA1GRIA2 | |
| SCHEMBL29637251 | 0.84 | SLC7A5 (0.43) | SLC7A5CYP3A4SLC1A3GRIA1GRIA2 | |
| SCHEMBL233541 | 0.84 | SLC7A5 (0.43) | SLC7A5CYP3A4SLC1A3GRIA1GRIA2 | |
| SCHEMBL27446953 | 0.84 | SLC7A5 (0.51) | SLC7A5CYP3A4SLC1A3GRIA1GRIA2 | |
| SCHEMBL8319666 | 0.83 | CYP3A4 (0.48) | SLC7A5CYP3A4SLC1A3GRIA1GRIA2 | |
| SCHEMBL4453505 | 0.81 | SLC7A5 (0.41) | SLC7A5CYP3A4SLC1A3GRIA1GRIA2 | |
| SCHEMBL27264186 | 0.81 | SLC7A5 (0.49) | SLC7A5CYP3A4SLC1A3GRIA1GRIA2 | |
| Methylamine SCHEMBL29022748 | 0.81 | CYP3A4 (0.46) | SLC7A5CYP3A4SLC1A3GRIA1GRIA2 | |
| SCHEMBL10403754 | 0.80 | SLC7A5 (0.48) | SLC7A5CYP3A4SLC1A3GRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463654-B1 | Compositions and methods for modeling saccharomyces cerevisiae metabolism | UNIV CALIFORNIA (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-2463654-A1 | Compositions and methods for modeling saccharomyces cerevisiae metabolism | The Regents of The University of California (US) | 2012-06-13 | — | — | EP | disclosed |
| US-8170852-B2 | Data structures and methods for modeling Saccharomyces cerevisiae metabolism | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-05-01 | — | — | US | disclosed |
| EP-2434421-A2 | Compositions and methods for modeling saccharomyces cerevisiae metabolism | The Regents of The University of California (US) | 2012-03-28 | — | — | EP | disclosed |
| US-20100280803-A1 | Compositions and Methods for Modeling Saccharomyces cerevisiae Metabolism | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2010-11-04 | — | — | US | disclosed |
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |
| US-7751981-B2 | Articles of manufacture and methods for modeling Saccharomyces cerevisiae metabolism | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-07-06 | — | — | US | disclosed |
| US-6020139-A | S-adenosyl methionine regulation of metabolic pathways and its use in diagnosis and therapy | ORIDIGM CORPORATION (US) | 2000-02-01 | — | — | US | disclosed |