Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | FURIN | P09958 | 2/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | NPY4R | P50391 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24270749 | 0.94 | FURIN (0.43) | FURINSIRT2SIRT1GRIA1HTT | |
| SCHEMBL21569760 | 0.93 | FURIN (0.47) | CTSLFURINSIRT2SIRT1SIRT3 | |
| SCHEMBL24829476 | 0.93 | FURIN (0.47) | CTSLFURINSIRT2SIRT1SIRT3 | |
| SCHEMBL15692124 | 0.93 | NMT2 (0.45) | CTSLFURINNPY1RNPY2RNPY4R | |
| SCHEMBL14978855 | 0.93 | NMT2 (0.45) | CTSLFURINNPY1RNPY2RNPY4R | |
| SCHEMBL25830860 | 0.92 | CTSL (0.43) | CTSLSIRT2SIRT1SIRT3GRIA1 | |
| SCHEMBL20839656 | 0.92 | NPY5R (0.42) | CTSLFURINNPY1RNPY2RNPY4R | |
| SCHEMBL22702533 | 0.91 | NPY5R (0.47) | CTSLSIRT2SIRT1SIRT3GRIA1 | |
| SCHEMBL23943639 | 0.91 | FURIN (0.44) | FURINSIRT2SIRT1SIRT3GRIA1 | |
| SCHEMBL17312902 | 0.90 | FURIN (0.41) | FURINSIRT1NPY1RNPY2RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820533-A2 | COMPOUNDS, COMPOSITIONS, METHODS, AND USES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | IL-2RX, Inc. (US) | 2021-05-19 | — | — | EP | disclosed |