Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22245786 | 0.87 | THRB (0.44) | PTGDRKMT2AMTNR1AMTNR1BMCL1 | |
| SCHEMBL20473155 | 0.84 | KMT2A (0.44) | PTGDRKMT2AMTNR1AMTNR1BMCL1 | |
| SCHEMBL20473148 | 0.83 | KMT2A (0.45) | PTGDRKMT2AMTNR1AMTNR1BMCL1 | |
| SCHEMBL23395595 | 0.79 | THRB (0.46) | KMT2AMTNR1AMTNR1BMCL1NR1H2 | |
| SCHEMBL20473145 | 0.76 | THRB (0.42) | PTGDRKMT2AMTNR1AMTNR1BMCL1 | |
| SCHEMBL21735691 | 0.75 | THRB (0.41) | KMT2AMTNR1AMTNR1BMCL1NR1H2 | |
| SCHEMBL30568049 | 0.74 | KMT2A (0.49) | KMT2AMTNR1AMTNR1BMCL1NR1H2 | |
| SCHEMBL20473383 | 0.74 | KMT2A (0.49) | KMT2AMTNR1AMTNR1BMCL1NR1H2 | |
| SCHEMBL30568044 | 0.74 | KMT2A (0.49) | KMT2AMTNR1AMTNR1BMCL1NR1H2 | |
| SCHEMBL22245883 | 0.73 | KMT2A (0.40) | KMT2AMTNR1AMTNR1BMCL1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3583098-B9 | HYDROPHILIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2021-05-12 | — | — | EP | disclosed |