Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22245789 | 0.88 | KMT2A (0.48) | KMT2ACYP19A1ALDH1A1KDM4EHPGD | |
| SCHEMBL20473148 | 0.88 | KMT2A (0.45) | KMT2APTGDRCYP19A1MTNR1AMTNR1B | |
| SCHEMBL22245786 | 0.86 | THRB (0.44) | KMT2APTGDRMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL23355162 | 0.84 | PTGDR (0.41) | KMT2APTGDRMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL20473383 | 0.78 | KMT2A (0.49) | KMT2AMTNR1AMTNR1BALDH1A1KDM4E | |
| SCHEMBL30568049 | 0.78 | KMT2A (0.49) | KMT2AMTNR1AMTNR1BALDH1A1KDM4E | |
| SCHEMBL30568044 | 0.78 | KMT2A (0.49) | KMT2AMTNR1AMTNR1BALDH1A1KDM4E | |
| SCHEMBL23395595 | 0.78 | THRB (0.46) | KMT2AMTNR1AMTNR1BALDH1A1HPGD | |
| SCHEMBL22245883 | 0.77 | KMT2A (0.40) | KMT2ACYP19A1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL22245988 | 0.75 | NR1H2 (0.50) | KMT2AALDH1A1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014900-B2 | Hydrophilic compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-25 | — | — | US | disclosed |
| US-11014900-B2 | Hydrophilic compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-25 | — | — | US | disclosed |
| EP-3583098-B9 | HYDROPHILIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2021-05-12 | — | — | EP | disclosed |
| EP-3583098-B9 | HYDROPHILIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2021-05-12 | — | — | EP | disclosed |
| EP-3583098-B1 | HYDROPHILIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-10-28 | — | — | EP | disclosed |
| EP-3583098-B1 | HYDROPHILIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-10-28 | — | — | EP | disclosed |
| US-20200231559-A1 | HYDROPHILIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-07-23 | — | — | US | disclosed |
| US-20200231559-A1 | HYDROPHILIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-07-23 | — | — | US | disclosed |
| EP-3363791-A1 | HYDROPHILIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | Merck Patent GmbH (DE) | 2018-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231559-A1 | HYDROPHILIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | AQP1, AQP3, AQP4 | KMT2A 4122/4885PTGDR 278/4885CYP19A1 2733/4885 |
| US-11014900-B2 | Hydrophilic compounds for optically active devices | AQP1, AQP3, AQP4 | KMT2A 4122/4885PTGDR 278/4885CYP19A1 2733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.