SCHEMBL2335535

SCHEMBL2335535

CCCC(N)(CCC)C(O)CO

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.34
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
CYP2D6 P10635 2/20 0.30
LMNA P02545 2/20 0.30
SPHK1 Q9NYA1 1/20 0.30
GMNN O75496 1/20 0.30
POLB P06746 1/20 0.30
THPO P40225 1/20 0.30
MTOR P42345 1/20 0.30
BLM P54132 1/20 0.30
KDM4E B2RXH2 1/20 0.30
TP53 P04637 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
CETP P11597 1/20 0.30
HTT P42858 1/20 0.30
UBE2N P61088 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3798895 0.84 FDPS (0.41) FDPSCYP2D6LMNASPHK1GMNN
SCHEMBL14949496 0.80 FDPS (0.34) FDPSTSHRLMNA
SCHEMBL2337550 0.79 TSHR (0.33) TSHRTDP1
Water SCHEMBL1334081 0.78 FDPS (0.33) FDPS
SCHEMBL11172593 0.75 FDPS (0.38) FDPSCYP2D6LMNASPHK1GMNN
SCHEMBL6847319 0.75 FDPS (0.31) FDPS
SCHEMBL22042797 0.73 TSHR (0.36) FDPSTSHR
SCHEMBL4395971 0.73 FDPS (0.39) FDPSCYP2D6LMNASPHK1GMNN
SCHEMBL27741017 0.73 LMNA (0.37) TDP1LMNA
SCHEMBL8533130 0.72 TSHR (0.38) TSHRTDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2912216-A1 DYEABLE AND FLAME-RETARDED THERMOPLASTIC POLYURETHANE FIBERS Lubrizol Advanced Materials, Inc. (US) 2015-09-02 EP disclosed
WO-2014066037-A1 DYEABLE AND FLAME-RETARDED THERMOPLASTIC POLYURETHANE FIBERS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2014-05-01 WO disclosed
EP-1201644-B1 A process for the prepraration of a dihydroxyamino compound DAICEL CHEM (JP) 2011-08-24 EP disclosed
EP-1201644-A2 A process for the prepration of a dihydroxyamino compound Daicel Chemical Industries, Ltd. (JP) 2002-05-02 EP disclosed
US-5874624-A REACTING EPOXY COMPOUND AND AN AMINO COMPOUND AT A SPECIFIED TEMPERATURE AND PRESSURE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-02-23 US disclosed
EP-0839802-A2 A process for the preparation of a dihydroxyamino compound DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1998-05-06 EP disclosed