Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30933439 | 0.92 | ALDH1A1 (0.36) | KMT2ASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL23355444 | 0.92 | ALDH1A1 (0.36) | KMT2ASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL23355480 | 0.84 | KMT2A (0.37) | KMT2ASMN1; SMN2NPC1CASP3RAB9A | |
| SCHEMBL24251609 | 0.84 | KMT2A (0.37) | KMT2ASMN1; SMN2NPC1CASP3RAB9A | |
| SCHEMBL23355473 | 0.83 | KMT2A (0.36) | KMT2ASMN1; SMN2NPC1CASP3RAB9A | |
| SCHEMBL23355436 | 0.73 | JAK1 (0.39) | KMT2ASMN1; SMN2NPC1RAB9APDE4B | |
| SCHEMBL23355434 | 0.73 | GAA (0.46) | KMT2AL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL23355438 | 0.72 | PDE4B (0.35) | PDE4BPDE4DELANERORCALDH1A1 | |
| SCHEMBL26632152 | 0.69 | SLC6A4 (0.45) | KMT2ASMN1; SMN2NPC1CASP3RAB9A | |
| SCHEMBL24251587 | 0.68 | HPGD (0.44) | KMT2ASMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996788-B | Anthelmintic heterocyclic compounds | 勃林格殷格翰动物保健美国公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-112996788-A | Anthelmintic heterocyclic compounds | 勃林格殷格翰动物保健美国公司 | 2021-06-18 | — | — | CN | disclosed |
| EP-3820870-A1 | ANTHELMINTHIC HETEROCYCLIC COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-05-19 | — | — | EP | disclosed |