Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23355447 | 0.92 | MAPK14 (0.43) | JAK1TYK2KMT2AALDH1A1OPRM1 | |
| SCHEMBL30933433 | 0.92 | MAPK14 (0.43) | JAK1TYK2KMT2AALDH1A1OPRM1 | |
| SCHEMBL29273408 | 0.86 | TTR (0.45) | KMT2AALDH1A1MAPK14NPC1MAPT | |
| SCHEMBL29273416 | 0.78 | RORC (0.41) | CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23355474 | 0.76 | TDP1 (0.42) | KMT2AALDH1A1OPRM1MAPK14KDM4E | |
| SCHEMBL23355443 | 0.73 | KMT2A (0.38) | KMT2AALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL23355462 | 0.72 | KDM4E (0.45) | KMT2AALDH1A1KDM4ENPC1HTT | |
| SCHEMBL23355480 | 0.71 | KMT2A (0.37) | KMT2AALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL24251609 | 0.71 | KMT2A (0.37) | KMT2AALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL23355473 | 0.71 | KMT2A (0.36) | KMT2AALDH1A1KDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250243197-A1 | Anthelmintic Heterocyclic Compounds | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2025-07-31 | — | — | US | disclosed |
| US-12269822-B2 | Anthelminthic heterocyclic compounds | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2025-04-08 | — | — | US | disclosed |
| CN-112996788-B | Anthelmintic heterocyclic compounds | 勃林格殷格翰动物保健美国公司 | 2024-07-16 | — | — | CN | disclosed |
| US-20220048903-A1 | Anthelminthic Heterocyclic Compounds | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2022-02-17 | — | — | US | disclosed |
| US-20220048903-A1 | Anthelminthic Heterocyclic Compounds | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2022-02-17 | — | — | US | disclosed |
| CN-112996788-A | Anthelmintic heterocyclic compounds | 勃林格殷格翰动物保健美国公司 | 2021-06-18 | — | — | CN | disclosed |
| EP-3820870-A1 | ANTHELMINTHIC HETEROCYCLIC COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048903-A1 | Anthelminthic Heterocyclic Compounds | SDHA, PAH, PIGS | JAK1 3245/4885TYK2 4263/4885KMT2A 1440/4885 |
| US-12269822-B2 | Anthelminthic heterocyclic compounds | SDHA, PAH, PIGS | JAK1 3245/4885TYK2 4263/4885KMT2A 1440/4885 |
| US-20250243197-A1 | Anthelmintic Heterocyclic Compounds | PAH, PIGS, SDHA | JAK1 3386/4885TYK2 4323/4885KMT2A 1729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.