Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2785439 | 0.87 | EPHX2 (0.44) | EPHX2ALDH1A1LMNANPSR1NPC1 | |
| SCHEMBL2332078 | 0.87 | EPHX2 (0.44) | EPHX2ALDH1A1LMNANPSR1NPC1 | |
| SCHEMBL2340470 | 0.87 | EPHX2 (0.44) | EPHX2ALDH1A1LMNANPSR1NPC1 | |
| SCHEMBL2331584 | 0.77 | ALDH1A1 (0.46) | EPHX2ALDH1A1LMNANPC1ALPL | |
| SCHEMBL2331330 | 0.77 | ALDH1A1 (0.46) | EPHX2ALDH1A1LMNANPC1ALPL | |
| SCHEMBL2331329 | 0.77 | ALDH1A1 (0.46) | EPHX2ALDH1A1LMNANPC1ALPL | |
| SCHEMBL5510913 | 0.72 | CLCN2 (0.48) | ALDH1A1POLBMMEMEN1KMT2A | |
| SCHEMBL26703141 | 0.71 | EPHX2 (0.41) | EPHX2ALDH1A1LMNANPSR1NPC1 | |
| SCHEMBL2330887 | 0.71 | NPC1 (0.40) | EPHX2ALDH1A1NPC1ALPLALPI | |
| SCHEMBL2336190 | 0.71 | NPC1 (0.40) | EPHX2ALDH1A1NPC1ALPLALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2360160-A1 | Intermediates and their use for producing benzoxazine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-08-24 | — | — | EP | disclosed |