Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331330 | 1.00 | ALDH1A1 (0.46) | ALDH1A1NPC1POLBSMN1; SMN2LMNA | |
| SCHEMBL2331584 | 1.00 | ALDH1A1 (0.46) | ALDH1A1NPC1POLBSMN1; SMN2LMNA | |
| SCHEMBL2339531 | 0.87 | LMNA (0.42) | ALDH1A1NPC1POLBSMN1; SMN2LMNA | |
| Cyclohexylamine SCHEMBL2331574 | 0.85 | EPHX2 (0.47) | ALDH1A1NPC1POLBSMN1; SMN2LMNA | |
| SCHEMBL17646176 | 0.84 | SMN1; SMN2 (0.54) | ALDH1A1NPC1SMN1; SMN2LMNARAB9A | |
| SCHEMBL17260383 | 0.84 | SMN1; SMN2 (0.54) | ALDH1A1NPC1SMN1; SMN2LMNARAB9A | |
| SCHEMBL2339438 | 0.83 | POLB (0.49) | ALDH1A1NPC1POLBSMN1; SMN2LMNA | |
| SCHEMBL2334831 | 0.83 | POLB (0.49) | ALDH1A1NPC1POLBSMN1; SMN2LMNA | |
| SCHEMBL2337104 | 0.83 | POLB (0.49) | ALDH1A1NPC1POLBSMN1; SMN2LMNA | |
| SCHEMBL2332078 | 0.79 | EPHX2 (0.44) | ALDH1A1NPC1POLBLMNAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1211254-B1 | Process for the preparation of benzoxazine derivatives and intermediates therefor | DAIICHI SANKYO CO LTD (JP) | 2014-05-07 | — | — | EP | disclosed |
| EP-2284174-B1 | Intermediates for the preparation of benzoxazine derivatives and process for their preparation | DAIICHI SANKYO CO LTD (JP) | 2014-03-05 | — | — | EP | disclosed |
| EP-2360160-B1 | Intermediates and their use for producing benzoxazine derivative | DAIICHI SANKYO CO LTD (JP) | 2013-07-24 | — | — | EP | disclosed |
| EP-2218722-B9 | Process for producing benzoxazine derivative and production intermediate thereof | DAIICHI SANKYO CO LTD (JP) | 2013-06-19 | — | — | EP | disclosed |
| EP-2218722-B1 | Process for producing benzoxazine derivative and production intermediate thereof | DAIICHI SANKYO CO LTD (JP) | 2013-03-13 | — | — | EP | disclosed |
| EP-2360160-A1 | Intermediates and their use for producing benzoxazine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-08-24 | — | — | EP | disclosed |
| EP-2284174-A1 | INTERMEDIATES FOR THE PREPARATION OF BENZOXAZINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | Daiichi Sankyo Company, Limited (JP) | 2011-02-16 | — | — | EP | disclosed |
| EP-2218722-A2 | Process for producing benzoxazine derivative and production intermediate thereof | Daiichi Sankyo Company, Limited (JP) | 2010-08-18 | — | — | EP | disclosed |
| US-7189847-B2 | Process for producing benzoxazine derivative and production intermediate thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-13 | — | — | US | disclosed |
| US-7087778-B2 | Process for producing benzoxazine derivative and production intermediate thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-08-08 | — | — | US | disclosed |
| US-20060014947-A1 | Process for producing benzoxazine derivative and production intermediate thereof | DAIICHI PHARMACEUTICAL CO., LTD. | 2006-01-19 | — | — | US | disclosed |
| US-6872823-B1 | Process for producing benzoxazine derivative and production intermediate thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-03-29 | — | — | US | disclosed |
| US-20050027119-A1 | Process for producing benzoxazine derivative and production intermediate thereof | DAIICHI PHARMACEUTICAL CO., LTD. | 2005-02-03 | — | — | US | disclosed |
| EP-1211254-A1 | PROCESS FOR THE PREPARATION OF BENZOXAZINE DERIVATIVES AND INTERMEDIATES THEREFOR | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-06-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014947-A1 | Process for producing benzoxazine derivative and production intermediate thereof | CYP4Z1, COASY, VAT1 | ALDH1A1 393/4885NPC1 4315/4885POLB 851/4885 |
| US-20050027119-A1 | Process for producing benzoxazine derivative and production intermediate thereof | CYP4Z1, COASY, VAT1 | ALDH1A1 299/4885NPC1 4274/4885POLB 1511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.