Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1712413 | 0.87 | CHKA (0.51) | S1PR1DRD2MAPTITGB3ITGA2B | |
| SCHEMBL23780016 | 0.81 | MAPT (0.41) | DRD2MAPTITGB3ITGA2BDRD3 | |
| SCHEMBL4574889 | 0.80 | DRD4 (0.54) | DRD2MAPTDRD3LMNADRD4 | |
| SCHEMBL1018073 | 0.77 | MAPT (0.61) | MAPTNPSR1LMNAMEN1ALDH1A1 | |
| SCHEMBL1412431 | 0.76 | CHRNA7 (0.58) | HTR1ADRD2MAPTSIGMAR1DRD3 | |
| SCHEMBL4809382 | 0.76 | CHKA (0.51) | MAPTNPSR1CHKAMEN1ALDH1A1 | |
| SCHEMBL17923026 | 0.76 | ALDH1A1 (0.46) | HTR1AMAPTSIGMAR1HTR2ATMEM97 | |
| SCHEMBL15392533 | 0.75 | CHKA (0.65) | MAPTNPSR1LMNACHKAALDH1A1 | |
| SCHEMBL12676672 | 0.74 | CHKA (0.53) | MAPTNPSR1CHKAMEN1ALDH1A1 | |
| SCHEMBL23355635 | 0.74 | S1PR1 (0.36) | S1PR1HTR1ADRD2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820474-A1 | ADENOSINE RECEPTOR BINDING COMPOUNDS | Nikang Therapeutics, Inc. (US) | 2021-05-19 | — | — | EP | disclosed |