Methane

Methane

SCHEMBL23355698

C.O=S1(=O)c2ccc(cc2)CC2CNCCN21

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 20/20 0.35
HTR2B P41595 19/20 0.35
HTR2A P28223 18/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3554115 0.72 HTR2C (0.49) HTR2CHTR2BHTR2A
SCHEMBL3550826 0.65 HTR2C (0.56) HTR2CHTR2BHTR2A
SCHEMBL13595229 0.63 KEAP1 (0.39) HTR2CHTR2BHTR2A
Oxirane SCHEMBL608361 0.62 HTR6 (0.36) HTR2CHTR2BHTR2A
SCHEMBL17062800 0.60 HTR2C (0.36) HTR2CHTR2BHTR2A
SCHEMBL11946506 0.60 HPGD (0.37) HTR2CHTR2BHTR2A
SCHEMBL117103 0.59 HTR6 (0.42) HTR2CHTR2B
SCHEMBL2419694 0.59 HTR6 (0.42) HTR2CHTR2B
Hydrochloric Acid SCHEMBL14324682 0.58 HTR6 (0.41)
SCHEMBL22440326 0.58 HTR6 (0.33) HTR2CHTR2BHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3820474-A1 ADENOSINE RECEPTOR BINDING COMPOUNDS Nikang Therapeutics, Inc. (US) 2021-05-19 EP disclosed