SCHEMBL2335903

SCHEMBL2335903

CCCCC(CC)C(=O)OOC(C)(CC(C)C)OOC(=O)C(CC)CCCC

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.53
CA1 P00915 4/20 0.53
MAPK1 P28482 1/20 0.44
ATM Q13315 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
GAA P10253 1/20 0.39
XBP1 P17861 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TSHR P16473 3/20 0.34
CYP3A4 P08684 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MMP8 P22894 1/20 0.33
USP2 O75604 1/20 0.33
CTSK P43235 1/20 0.33
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL249395 0.93 CA2 (0.46) CA2CA1MAPK1ATML3MBTL1
SCHEMBL6844550 0.93 CA2 (0.46) CA2CA1MAPK1ATML3MBTL1
SCHEMBL7879155 0.93 CA2 (0.49) CA2CA1MAPK1ATML3MBTL1
SCHEMBL3747655 0.89 MMP8 (0.38) CA2CA1MAPK1MMP8
SCHEMBL11051590 0.85 CA2 (0.58) CA2CA1MAPK1ATML3MBTL1
SCHEMBL6846544 0.84 CA2 (0.46) CA2CA1MAPK1ATML3MBTL1
SCHEMBL20299539 0.84 CA2 (0.56) CA2CA1MAPK1ATML3MBTL1
SCHEMBL8729030 0.83 CA2 (0.51) CA2CA1MAPK1ATML3MBTL1
SCHEMBL2049913 0.83 CA2 (0.51) CA2CA1MAPK1ATML3MBTL1
SCHEMBL218700 0.82 CA2 (0.58) CA2CA1MAPK1ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1456257-B2 ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION AKZO NOBEL CHEMICALS INT BV (NL) 2020-04-01 EP disclosed
EP-1636272-B2 POLYMERIZATION PROCESS INVOLVING THE DOSING INITIATORS AKZO NOBEL NV (NL) 2011-08-17 EP disclosed
US-7834110-B2 Polymerization in presence of promoters and surfactant; overall polymerization time is reduced by a reduction of the pressure drop time AKZO NOBEL N. V. (NL) 2010-11-16 US disclosed
EP-1456257-B1 ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION AKZO NOBEL NV (NL) 2009-06-24 EP disclosed
US-20080221266-A1 Polymerization in presence of promoters and surfactant; overall polymerization time is reduced by a reduction of the pressure drop time AKZO NOBEL N.V. (NL) 2008-09-11 US disclosed
EP-1636272-B1 POLYMERIZATION PROCESS INVOLVING THE DOSING INITIATORS AKZO NOBEL NV (NL) 2007-12-05 EP disclosed
US-7173095-B2 Polymerization process involving the dosing initiators AKZO NOBEL N. V. (NL) 2007-02-06 US disclosed
US-7109275-B2 Co-metering of organic initiators and protective colloids during polymerization reactions AKZO NOBEL N.V. (NL) 2006-09-19 US disclosed
EP-1495057-B1 CO-METERING OF ORGANIC INITIATORS AND PROTECTIVE COLLOIDS DURING POLYMERIZATION REACTIONS AKZO NOBEL NV (NL) 2006-08-02 EP disclosed
US-7078553-B2 Dehydrohalogenation by reacting a di-hydroperoxy compound with an acid halogen or halogen formate to form mono- or di-peroxy ester or carbonate; polymerization initiators, curing agents for unsaturated polyesters and modifying agents AKZO NOBEL N.V. (NL) 2006-07-18 US disclosed
EP-1375529-A1 Addition of organic initiators during a pressure drop in vinyl chloride monomer polymerization reactions Akzo Nobel N.V. (NL) 2004-01-02 EP disclosed
WO-2003087168-A1 CO-METERING OF ORGANIC INITIATORS AND PROTECTIVE COLLOIDS DURING POLYMERIZATION REACTIONS AKZO NOBEL N.V. (NL) 2003-10-23 WO disclosed
US-20030199656-A1 Co-metering of organic initiators and protective colloids during polymerization reactions WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) 2003-10-23 US disclosed
WO-2003054039-A1 ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION REACTIONS AKZO NOBEL N.V. (NL) 2003-07-03 WO disclosed
US-6552215-B1 Reacting a hydroperoxy compound containing a peroxyester or peroxycarbonate functionality with an alkyl vinyl ether; polymerization initiators, curing agents for unsaturated polyesters and modifying agents AKZO NOBEL N.V. (NL) 2003-04-22 US disclosed
EP-1049668-B1 KETONE PEROXIDE DERIVATIVES, THEIR PREPARATION AND USE AKZO NOBEL NV (NL) 2003-03-19 EP disclosed
EP-1144461-A1 AQUEOUS PEROXIDE EMULSIONS Akzo Nobel N.V. (NL) 2001-10-17 EP disclosed
EP-1049668-A1 KETONE PEROXIDE DERIVATIVES, THEIR PREPARATION AND USE Akzo Nobel N.V. (NL) 2000-11-08 EP disclosed
WO-2000042078-A1 AQUEOUS PEROXIDE EMULSIONS AKZO NOBEL N.V. (NL) 2000-07-20 WO disclosed
WO-1999032442-A1 KETONE PEROXIDE DERIVATIVES, THEIR PREPARATION AND USE AKZO NOBEL N.V. (NL) 1999-07-01 WO disclosed