SCHEMBL2336138

SCHEMBL2336138

Nc1c(Br)cc2c(sc3ccccc32)c1Br

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.46
RAB9A P51151 3/20 0.46
ALDH1A1 P00352 3/20 0.46
HPGD P15428 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
GPR3 P46089 1/20 0.45
PTPN1 P18031 2/20 0.42
LIMK1 P53667 2/20 0.40
CDK5 Q00535 1/20 0.40
CDK5R1 Q15078 1/20 0.40
TNKS O95271 1/20 0.40
TNKS2 Q9H2K2 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
ATM Q13315 2/20 0.39
KDM4E B2RXH2 2/20 0.39
IKBKB O14920 1/20 0.39
HKDC1 Q2TB90 1/20 0.39
TDO2 P48775 1/20 0.38
CTSB P07858 1/20 0.37
ALOX5 P09917 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19607175 0.85 MAPT (0.46) MAPTRAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL19607174 0.85 MAPT (0.42) MAPTRAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL1294718 0.79 GPR3 (0.50) MAPTRAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL30340721 0.79 GPR3 (0.50) MAPTRAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL20441721 0.79 PTPN1 (0.60) MAPTRAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL17987488 0.79 MAPT (0.50) MAPTRAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL22172094 0.76 PTPN1 (0.50) MAPTRAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL5028205 0.76 MAPT (0.47) MAPTRAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL16867080 0.76 PTPN1 (0.47) MAPTRAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL23589564 0.76 ALOX5 (0.55) MAPTRAB9AALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2539913-B1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORP (US) 2017-09-27 EP disclosed
EP-2539913-B1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORP (US) 2017-09-27 EP disclosed
US-9156870-B2 Phosphorescent emitters UNIVERSAL DISPLAY CORPORATION (US) 2015-10-13 US disclosed
US-9156870-B2 Phosphorescent emitters UNIVERSAL DISPLAY CORPORATION (US) 2015-10-13 US disclosed
US-9156870-B2 Phosphorescent emitters UNIVERSAL DISPLAY CORPORATION (US) 2015-10-13 US disclosed
EP-2539913-A1 PHOSPHORESCENT EMITTERS Universal Display Corporation (US) 2013-01-02 EP disclosed
WO-2011106344-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2011-09-01 WO disclosed
WO-2011106344-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2011-09-01 WO disclosed
US-20110204333-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2011-08-25 US disclosed
US-20110204333-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2011-08-25 US disclosed
US-20110204333-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2011-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110204333-A1 PHOSPHORESCENT EMITTERS TEC, IK, DDT MAPT 165/4885RAB9A 724/4885ALDH1A1 2042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.