Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | MAX | P61244 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693313 | 0.90 | BACE1 (0.45) | BACE1MAPTARMEN1KMT2A | |
| SCHEMBL16406418 | 0.87 | ALDH1A1 (0.48) | BACE1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL4912305 | 0.86 | BACE1 (0.49) | BACE1MAPTARMEN1KMT2A | |
| SCHEMBL9893444 | 0.86 | MEN1 (0.57) | BACE1MAPTARMEN1KMT2A | |
| SCHEMBL9893345 | 0.85 | MAPT (0.50) | BACE1MAPTARMEN1KMT2A | |
| SCHEMBL9893373 | 0.84 | BACE1 (0.50) | BACE1MAPTARMEN1KMT2A | |
| SCHEMBL5579639 | 0.82 | CTSV (0.55) | BACE1MAPTARMEN1KMT2A | |
| SCHEMBL2337924 | 0.80 | BACE1 (0.49) | BACE1MAPTARMEN1KMT2A | |
| SCHEMBL30832846 | 0.80 | MEN1 (0.57) | BACE1MAPTARMEN1KMT2A | |
| SCHEMBL1663438 | 0.80 | MEN1 (0.57) | BACE1MAPTARMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |