Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 9/20 | 0.56 |
| ▸ | RXRB | P28702 | 8/20 | 0.56 |
| ▸ | RXRG | P48443 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30495975 | 1.00 | RXRA (0.56) | RXRARXRBRXRGHPGDFOLH1 | |
| SCHEMBL23383976 | 0.87 | RXRA (0.70) | RXRARXRBRXRGHPGDFOLH1 | |
| SCHEMBL21798467 | 0.84 | RXRA (0.70) | RXRARXRBRXRGHPGDFOLH1 | |
| Tucaresol SCHEMBL29400654 | 0.83 | RXRA (0.56) | RXRARXRBRXRGHPGDFOLH1 | |
| Tucaresol SCHEMBL600942 | 0.83 | RXRA (0.56) | RXRARXRBRXRGHPGDFOLH1 | |
| SCHEMBL6026702 | 0.81 | BRD4 (0.59) | RXRARXRBRXRGHPGDFOLH1 | |
| SCHEMBL17826400 | 0.80 | FOLH1 (0.54) | RXRARXRBRXRGHPGDFOLH1 | |
| SCHEMBL23384170 | 0.79 | RXRA (0.51) | RXRARXRBRXRGHPGDFOLH1 | |
| SCHEMBL10923656 | 0.79 | TP53 (0.54) | HPGDFOLH1PTGER1KDM4EKMT2A | |
| SCHEMBL6341223 | 0.78 | KMT2A (0.66) | RXRARXRBRXRGHPGDPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778155-B | Tucarbaryl derivatives and uses thereof | 大连万春布林医药有限公司 | 2023-08-11 | — | — | CN | disclosed |
| US-20220387365-A1 | TUCARESOL DERIVATIVES AND USES THEREOF | BEYONDSPRING PHARMACEUTICALS, INC. | 2022-12-08 | — | — | US | disclosed |
| US-20220387365-A1 | TUCARESOL DERIVATIVES AND USES THEREOF | BEYONDSPRING PHARMACEUTICALS, INC. | 2022-12-08 | — | — | US | disclosed |
| EP-4058427-A1 | TUCARESOL DERIVATIVES AND USES THEREOF | Beyondspring Pharmaceuticals Inc. (US) | 2022-09-21 | — | — | EP | disclosed |
| WO-2021096811-A1 | TUCARESOL DERIVATIVES AND USES THEREOF | BEYONDSPRING PHARMACEUTICALS, INC. (US) | 2021-05-20 | — | — | WO | disclosed |
| WO-2021096811-A1 | TUCARESOL DERIVATIVES AND USES THEREOF | BEYONDSPRING PHARMACEUTICALS, INC. (US) | 2021-05-20 | — | — | WO | disclosed |
| CN-112778155-A | Turcatecol derivatives and uses thereof | 万春药业公司 | 2021-05-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220387365-A1 | TUCARESOL DERIVATIVES AND USES THEREOF | ICOS, TEX264, PBK | RXRA 1594/4885RXRB 1704/4885RXRG 1707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.