Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 6/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4194315 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL31099330 | 0.74 | CYP2D6 (0.37) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL26918754 | 0.73 | CHRNB2 (0.30) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL26423433 | 0.72 | CHRM1 (0.38) | CHRM1BCHE | |
| SCHEMBL4779449 | 0.72 | CHRM1 (0.41) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL19733547 | 0.72 | CHRM1 (0.38) | CHRM1BCHE | |
| SCHEMBL28417988 | 0.72 | CHRM1 (0.41) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL21144296 | 0.71 | ATM (0.32) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL26099346 | 0.71 | ATM (0.32) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL26099348 | 0.71 | ATM (0.32) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021097061-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2021-05-20 | — | — | WO | disclosed |