Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | FABP7 | O15540 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24180284 | 0.88 | ALDH1A1 (0.53) | SMN1; SMN2NPC1RAB9AALDH1A1GAA | |
| SCHEMBL7642406 | 0.85 | ALDH1A1 (0.55) | SMN1; SMN2NPC1RAB9AALDH1A1GAA | |
| SCHEMBL17391167 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AALDH1A1GAA | |
| SCHEMBL12856110 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AALDH1A1GAA | |
| SCHEMBL13865266 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AALDH1A1GAA | |
| SCHEMBL17391166 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AALDH1A1GAA | |
| SCHEMBL12856117 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AALDH1A1GAA | |
| SCHEMBL23963805 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AALDH1A1GAA | |
| SCHEMBL7639964 | 0.82 | FKBP1A (0.50) | SMN1; SMN2NPC1RAB9AALDH1A1GAA | |
| SCHEMBL304689 | 0.82 | FKBP1A (0.53) | SMN1; SMN2NPC1RAB9AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11007274-B2 | Compounds for medicinal applications | AusVir Therapeutics Pty Ltd (AU) | 2021-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11007274-B2 | Compounds for medicinal applications | HAVCR2, ENGASE, DNPEP | SMN1; SMN2 4112/4885NPC1 890/4885RAB9A 1747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.