SCHEMBL2336706

SCHEMBL2336706

COc1ccc(CC(=O)N(O)Cc2ccccc2)cc1OC

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 7/20 0.59
BCHE P06276 6/20 0.59
L3MBTL1 Q9Y468 1/20 0.57
ALOX5 P09917 2/20 0.56
KMT2A Q03164 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2C19 P33261 1/20 0.54
TAS2R14 Q9NYV8 1/20 0.52
OPRD1 P41143 1/20 0.50
OPRK1 P41145 1/20 0.50
CTSD P07339 1/20 0.49
POLB P06746 1/20 0.49
LDHA P00338 1/20 0.49
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2341738 0.88 LMNA (0.47) ACHEBCHEL3MBTL1KMT2APOLB
SCHEMBL16930319 0.79 CYP1A2 (0.66) ACHEBCHEL3MBTL1KMT2ACYP1A2
SCHEMBL10948188 0.77 LMNA (0.56) L3MBTL1KMT2ACYP1A2CYP3A4LDHA
SCHEMBL6993505 0.76 L3MBTL1 (0.58) L3MBTL1KMT2AOPRK1ALDH1A1
SCHEMBL9416534 0.76 MEN1 (0.64) KMT2ACYP1A2CYP3A4MEN1
SCHEMBL153055 0.75 GAA (0.74) KMT2ACYP1A2CYP3A4CYP2C19LDHA
SCHEMBL30049382 0.75 GAA (0.74) KMT2ACYP1A2CYP3A4CYP2C19LDHA
SCHEMBL11003187 0.75 APP (0.55) ACHEBCHEL3MBTL1KMT2ALDHA
SCHEMBL1515840 0.75 LMNA (0.54) ACHEBCHEL3MBTL1KMT2ACYP1A2
SCHEMBL570575 0.75 LMNA (0.75) ACHEBCHEL3MBTL1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9210928-B2 Plant development control composition SYNGENTA CROP PROTECTION, LLC (US) 2015-12-15 US disclosed
US-20110301028-A1 PLANT DEVELOPMENT CONTROL COMPOSITION SYNGENTA CROP PROTECTION, LLC (US) 2011-12-08 US disclosed
EP-2358197-A2 PLANT DEVELOPMENT CONTROL COMPOSITION Syngenta Participations AG (CH) 2011-08-24 EP disclosed
WO-2010055316-A2 PLANT DEVELOPMENT CONTROL COMPOSITION THE UNIVERSITY OF WARWICK (GB) 2010-05-20 WO disclosed
WO-2010055310-A1 HERBICIDAL COMPOSITIONS THE UNIVERSITY OF WARWICK (GB) 2010-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110301028-A1 PLANT DEVELOPMENT CONTROL COMPOSITION MSL1, OXSR1, OSR1 ACHE 3601/4885BCHE 3722/4885L3MBTL1 254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.