Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 5/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.36 |
| ▸ | TERT | O14746 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12717778 | 0.82 | S1PR1 (0.49) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL5047334 | 0.82 | S1PR1 (0.48) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL23645217 | 0.77 | S1PR1 (0.49) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL24577734 | 0.77 | S1PR1 (0.49) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| Delmopinol SCHEMBL20298306 | 0.77 | PDK1 (0.33) | — | |
| Delmopinol SCHEMBL120704 | 0.77 | PDK1 (0.33) | — | |
| SCHEMBL3429337 | 0.77 | TERT (0.46) | S1PR1S1PR3S1PR5S1PR4TERT | |
| SCHEMBL3429301 | 0.77 | TERT (0.46) | S1PR1S1PR3S1PR5S1PR4TERT | |
| SCHEMBL3429412 | 0.77 | TERT (0.46) | S1PR1S1PR3S1PR5S1PR4TERT | |
| SCHEMBL5967889 | 0.76 | S1PR1 (0.57) | S1PR1S1PR3S1PR5S1PR4SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672945-B1 | SALTS OF DELMOPINOL | LUNDBECK PHARMACEUTICALS ITALY S P A (IT) | 2022-01-05 | — | — | EP | disclosed |
| EP-3558953-B1 | METHOD FOR THE MANUFACTURING OF 2-(3-(ALKYL AND ALKENYL)MORPHOLINO)-ETHAN-1-OLS | LUNDBECK PHARMACEUTICALS ITALY S P A (IT) | 2021-05-19 | — | — | EP | disclosed |