Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23367285 | 0.85 | CA1 (0.42) | KMT2ARAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL23367425 | 0.83 | ALDH1A1 (0.57) | KMT2ARAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL23354938 | 0.81 | KMT2A (0.44) | KMT2ARAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL518882 | 0.78 | KMT2A (0.47) | KMT2ARAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL23354723 | 0.75 | MAPK1 (0.44) | KMT2ARAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL23384997 | 0.74 | MEN1 (0.45) | KMT2ARAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL31312715 | 0.74 | KMT2A (0.43) | KMT2ARAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL23367274 | 0.74 | KMT2A (0.47) | KMT2ASMN1; SMN2LMNAMEN1MAPT | |
| SCHEMBL29874018 | 0.74 | KMT2A (0.47) | KMT2ASMN1; SMN2LMNAMEN1MAPT | |
| SCHEMBL3132943 | 0.73 | KMT2A (0.47) | KMT2ARAB9ANPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822265-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer AG (DE) | 2021-05-19 | — | — | EP | disclosed |