Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23367279 | 0.85 | KMT2A (0.45) | CA1NPC1LMNARAB9AMAPT | |
| SCHEMBL10836427 | 0.81 | NPC1 (0.40) | CA1CA14NPC1LMNARAB9A | |
| SCHEMBL23354713 | 0.81 | EGFR (0.43) | CA1CA14NPC1LMNARAB9A | |
| SCHEMBL23384997 | 0.80 | MEN1 (0.45) | CA1NPC1LMNARAB9AMAPT | |
| SCHEMBL5973463 | 0.75 | LMNA (0.44) | CA1CA14NPC1LMNARAB9A | |
| SCHEMBL27901180 | 0.75 | ALDH1A1 (0.41) | CA1CA14NPC1LMNARAB9A | |
| SCHEMBL5973460 | 0.75 | LMNA (0.44) | CA1CA14NPC1LMNARAB9A | |
| SCHEMBL502509 | 0.75 | MRGPRX4 (0.43) | CA1CA14NPC1LMNARAB9A | |
| SCHEMBL7826269 | 0.75 | MAPT (0.50) | CA1CA14NPC1LMNARAB9A | |
| SCHEMBL502510 | 0.75 | MRGPRX4 (0.43) | CA1CA14NPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822265-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer AG (DE) | 2021-05-19 | — | — | EP | disclosed |