Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 5/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | SCN4A | P35499 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.30 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23355349 | 0.75 | SCN4A (0.32) | CSNK1ECSNK1DSCN4A | |
| SCHEMBL348058 | 0.72 | RAB9A (0.38) | CNR1CNR2 | |
| SCHEMBL21616328 | 0.70 | SCN4A (0.37) | CSNK1ECSNK1DSCN4A | |
| SCHEMBL23368169 | 0.70 | FYN (0.30) | — | |
| SCHEMBL23368117 | 0.67 | HTR2A (0.30) | — | |
| SCHEMBL161438 | 0.66 | P2RX4 (0.39) | CSNK1ECSNK1DSCN4A | |
| SCHEMBL348418 | 0.66 | NOS1 (0.46) | — | |
| SCHEMBL21612791 | 0.64 | SCN4A (0.34) | CSNK1ECSNK1DSCN4A | |
| SCHEMBL23355324 | 0.63 | SCN4A (0.34) | CNR1CNR2SCN4A | |
| SCHEMBL23368130 | 0.62 | P2RX4 (0.36) | CSNK1ECSNK1DCNR1SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822263-A1 | BIARYL ETHER-TYPE QUINAZOLINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2021-05-19 | — | — | EP | disclosed |