Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 5/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25860508 | 1.00 | CYP2C9 (0.43) | CYP2C9ALDH1A1LMNAMAPTSLC6A3 | |
| SCHEMBL25860487 | 1.00 | CYP2C9 (0.43) | CYP2C9ALDH1A1LMNAMAPTSLC6A3 | |
| SCHEMBL20813121 | 0.82 | ALDH1A1 (0.39) | CYP2C9ALDH1A1LMNAMAPTSLC6A3 | |
| SCHEMBL20813086 | 0.82 | ALDH1A1 (0.39) | CYP2C9ALDH1A1LMNAMAPTSLC6A3 | |
| SCHEMBL23368628 | 0.77 | TDP1 (0.50) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL13205401 | 0.77 | KDM1A (0.37) | CYP2C9ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL23368823 | 0.76 | CYP2C9 (0.38) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL23368604 | 0.75 | ESR2 (0.55) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL20813129 | 0.75 | ESR2 (0.55) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL20813149 | 0.75 | ESR2 (0.55) | CYP2C9ALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3183242-B1 | SUBSTITUTED BICYCLIC COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-05-19 | — | — | EP | disclosed |