Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331646 | 1.00 | EPHX2 (0.40) | EPHX2ALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL2332922 | 1.00 | EPHX2 (0.40) | EPHX2ALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL2925241 | 0.92 | EPHX2 (0.36) | EPHX2HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL4230480 | 0.87 | EPHX2 (0.40) | EPHX2ALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL20496965 | 0.86 | EPHX2 (0.39) | EPHX2ALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL29278340 | 0.85 | EPHX2 (0.38) | EPHX2ALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL517314 | 0.85 | GABRP (0.41) | EPHX2ALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL29579375 | 0.84 | GSR (0.47) | MEN1KMT2A | |
| SCHEMBL4758907 | 0.84 | GSR (0.47) | MEN1KMT2A | |
| SCHEMBL3858559 | 0.84 | GSR (0.47) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2360188-B1 | HYALURONIC ACID DERIVATIVE AND PHARMACEUTICAL COMPOSITION THEREOF | NAT UNIV CORP TOKYO MED & DENT (JP) | 2014-09-17 | — | — | EP | disclosed |
| EP-2360188-A1 | HYALURONIC ACID DERIVATIVE AND PHARMACEUTICAL COMPOSITION THEREOF | National University Corporation Tokyo Medical and Dental University (JP) | 2011-08-24 | — | — | EP | disclosed |