SCHEMBL23370134

SCHEMBL23370134

CC(C)(C)OC(=O)NC/C(=C\F)COc1ccc(S(=O)(=O)Cn2ccccc2=O)cc1

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ AOC2 O75106 18/20 0.66
▸ MAOA P21397 2/20 0.43
▸ MAOB P27338 4/20 0.42
▸ CA12 O43570 1/20 0.40
▸ CA1 P00915 1/20 0.40
▸ CA2 P00918 1/20 0.40
▸ CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23370104 0.82 AOC2 (0.67) AOC2MAOAMAOB
SCHEMBL23370042 0.81 MAOB (0.64) AOC2MAOAMAOBCA12CA1
SCHEMBL23358606 0.80 AOC2 (1.00) AOC2MAOAMAOB
SCHEMBL23358603 0.80 AOC2 (1.00) AOC2MAOAMAOB
SCHEMBL24906961 0.80 AOC2 (0.67) AOC2MAOBCA12CA1CA2
SCHEMBL24295299 0.79 CA1 (0.63) AOC2MAOBCA12CA1CA2
SCHEMBL23852233 0.79 CA1 (0.63) AOC2MAOBCA12CA1CA2
SCHEMBL16767547 0.77 CA12 (0.47) AOC2MAOBCA12CA1CA2
SCHEMBL16767549 0.77 CA12 (0.47) AOC2MAOBCA12CA1CA2
SCHEMBL23370068 0.76 AOC2 (0.66) AOC2MAOBCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230026801-A1 SSAO INHIBITORS AND USE THEREOF ECCOGENE INC. 2023-01-26 — — US disclosed
US-20210147360-A1 SSAO INHIBITORS AND USE THEREOF ECCOGENE INC. 2021-05-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230026801-A1 SSAO INHIBITORS AND USE THEREOF SSB, HAO1, SORD AOC2 39/4885MAOA 17/4885MAOB 21/4885
US-20210147360-A1 SSAO INHIBITORS AND USE THEREOF SSB, HAO1, SORD AOC2 39/4885MAOA 17/4885MAOB 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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