Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 6/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24854026 | 0.92 | NPC1 (0.37) | NPC1RAB9ARXRAGRIN1GRIN2B | |
| SCHEMBL23370318 | 0.82 | CYP1A2 (0.35) | RXRAGRIN1GRIN2BL3MBTL1CYP1A2 | |
| SCHEMBL23370323 | 0.78 | CYP1A2 (0.35) | RXRAGRIN1GRIN2BL3MBTL1CYP1A2 | |
| SCHEMBL24853777 | 0.78 | HSP90AA1 (0.31) | RXRAGRIN1GRIN2BSLC9A1 | |
| SCHEMBL24853585 | 0.75 | RXRA (0.31) | RXRAGRIN1GRIN2B | |
| SCHEMBL24853578 | 0.74 | RXRA (0.31) | RXRAGRIN1GRIN2BCYP1A2CYP3A4 | |
| SCHEMBL23370331 | 0.73 | CYP1A2 (0.34) | RXRAGRIN1GRIN2BL3MBTL1CYP1A2 | |
| SCHEMBL23370440 | 0.73 | CYP1A2 (0.37) | RXRAGRIN1GRIN2BL3MBTL1CYP1A2 | |
| SCHEMBL29617951 | 0.73 | CDK9 (0.38) | RAB9AL3MBTL1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23361234 | 0.73 | NPC1 (0.43) | NPC1RAB9ASLC9A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021094416-A1 | 7-PYRIMIDINE-2-YL-OXY-INDAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2021-05-20 | — | — | WO | disclosed |