SCHEMBL23370381

SCHEMBL23370381

c1ccc(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4cc(-c6ccc7ccccc7c6)ccc4n5-c4ccccc4)ccc32)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
ATM Q13315 1/20 0.58
TUBB4A P04350 1/20 0.41
TUBB P07437 1/20 0.41
TUBA3C P0DPH7 1/20 0.41
TUBA1B P68363 1/20 0.41
TUBA4A P68366 1/20 0.41
TUBB4B P68371 1/20 0.41
TUBB3 Q13509 1/20 0.41
TUBB2A Q13885 1/20 0.41
TUBB8 Q3ZCM7 1/20 0.41
TUBA3E Q6PEY2 1/20 0.41
TUBA1A Q71U36 1/20 0.41
TUBA1C Q9BQE3 1/20 0.41
TUBB6 Q9BUF5 1/20 0.41
TUBB2B Q9BVA1 1/20 0.41
TUBB1 Q9H4B7 1/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18086156 1.00 KDM4E (0.58) KDM4EL3MBTL1ATMTUBB4ATUBB
SCHEMBL31450447 0.98 KDM4E (0.56) KDM4EL3MBTL1ATMTUBB4ATUBB
SCHEMBL18717930 0.98 KDM4E (0.56) KDM4EL3MBTL1ATMTUBB4ATUBB
SCHEMBL10130131 0.98 KDM4E (0.56) KDM4EL3MBTL1ATMTUBB4ATUBB
SCHEMBL18717914 0.97 KDM4E (0.55) KDM4EL3MBTL1ATMTUBB4ATUBB
SCHEMBL18789959 0.97 KDM4E (0.55) KDM4EL3MBTL1ATMTUBB4ATUBB
SCHEMBL16904431 0.97 KDM4E (0.55) KDM4EL3MBTL1ATMTUBB4ATUBB
SCHEMBL17228133 0.97 L3MBTL1 (0.62) KDM4EL3MBTL1ATMTUBB4ATUBB
SCHEMBL23370608 0.95 KDM4E (0.53) KDM4EL3MBTL1ATMTUBB4ATUBB
SCHEMBL23370390 0.95 KDM4E (0.53) KDM4EL3MBTL1ATMTUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230276704-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-08-31 US disclosed
EP-4234556-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL Chemical & Material Co., Ltd. (JP) 2023-08-30 EP disclosed
US-20210151683-A1 LIGHT-EMITTING ELEMENT, AND DISPLAY, ILLUMINATOR, AND SENSOR EACH INCLUDING SAME TORAY INDUSTRIES, INC. (JP) 2021-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230276704-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT ETV6, IKZF2, EML4 KDM4E 380/4885L3MBTL1 153/4885ATM 4641/4885
US-20210151683-A1 LIGHT-EMITTING ELEMENT, AND DISPLAY, ILLUMINATOR, AND SENSOR EACH INCLUDING SAME CBR3, INTS9, CBR1 KDM4E 1196/4885L3MBTL1 208/4885ATM 2844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.