Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2336820 | 0.88 | KMT2A (0.40) | ANPEPENPEPALDH1A1KMT2AMAPT | |
| SCHEMBL11469509 | 0.87 | ANPEP (0.46) | ANPEPENPEPALDH1A1KMT2AFOLH1 | |
| SCHEMBL3640935 | 0.85 | LOXL2 (0.47) | ALDH1A1KMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9843117 | 0.81 | ANPEP (0.59) | ANPEPENPEPALDH1A1KMT2ACA12 | |
| SCHEMBL2446964 | 0.80 | ANPEP (0.50) | ANPEPENPEPALDH1A1KMT2ACA12 | |
| SCHEMBL687298 | 0.80 | ANPEP (0.50) | ANPEPENPEPALDH1A1KMT2ACA12 | |
| SCHEMBL30789009 | 0.80 | ANPEP (0.50) | ANPEPENPEPALDH1A1KMT2ACA12 | |
| SCHEMBL13951835 | 0.80 | ANPEP (0.57) | ANPEPENPEPALDH1A1KMT2ACA12 | |
| SCHEMBL8658142 | 0.80 | ANPEP (0.53) | ANPEPENPEPALDH1A1CA12CA1 | |
| SCHEMBL28932021 | 0.80 | MAPT (0.47) | ANPEPALDH1A1KMT2AAKR1C3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358689-A1 | Benzothiazole derivatives as anticancer agents | Takeda Pharmaceutical Company Limited (JP) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010064722-A1 | BENZOTHIAZOLE DERIVATIVES AS ANTICANCER AGENTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-10 | — | — | WO | disclosed |
| EP-2162445-A1 | HETEROBICYCLIC COMPOUNDS AS KINASE INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2010-03-17 | — | — | EP | disclosed |
| EP-2049541-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008150015-A1 | HETEROBICYCLIC COMPOUNDS AS KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-11 | — | — | WO | disclosed |
| WO-2008016192-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-07 | — | — | WO | disclosed |
| US-4183944-A | ANALGESICS, ANTIPYRETICS, ANTICOAGULANTS, ANTIINFLAMMATORY AGENTS | RHONE POULENC INDUSTRIES (FR) | 1980-01-15 | — | — | US | disclosed |
| US-4124596-A | ANALGESICS, ANTIPYRETICS, ANTICLOTTING AGENTS, ANTIINFLAMMATORY AGENTS | RHONE-POULENC INDUSTRIES (FR) | 1978-11-07 | — | — | US | disclosed |