Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22069728 | 0.87 | KDM4E (0.74) | POLBKDM4EGAAKMT2AMEN1 | |
| SCHEMBL23373337 | 0.82 | GAA (0.64) | KDM4EGAAKMT2AMEN1LMNA | |
| SCHEMBL23373325 | 0.82 | KDM4E (0.60) | POLBKDM4EGAAKMT2AMEN1 | |
| SCHEMBL23373386 | 0.81 | MTNR1B (0.73) | KDM4EGAARECQL | |
| SCHEMBL22069671 | 0.80 | GAA (0.73) | KDM4EGAAKMT2ALMNAALDH1A1 | |
| SCHEMBL23373360 | 0.79 | POLB (0.70) | POLBKDM4EGAATDP1ALDH1A1 | |
| SCHEMBL9312707 | 0.78 | POLB (1.00) | POLBKDM4EKMT2AMEN1LMNA | |
| SCHEMBL9842944 | 0.77 | POLB (0.77) | POLBKDM4EGAAKMT2AMEN1 | |
| SCHEMBL29270204 | 0.77 | POLB (0.77) | POLBKDM4EKMT2AMEN1LMNA | |
| SCHEMBL12445438 | 0.77 | POLB (0.83) | POLBKDM4EKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021092893-A1 | USE OF DIARYL ETHER COMPOUND IN PREPARATION OF ANTI-TUMOR DRUG | 北京大学深圳研究生院 | 2021-05-20 | — | — | WO | disclosed |