Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 6/20 | 0.69 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.54 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5065450 | 0.85 | NCF1 (0.88) | NCF1ADRB2ADRB1HTTMAPK1 | |
| SCHEMBL6125246 | 0.84 | NCF1 (0.75) | NCF1ADRB2ADRB1HTTMAPK1 | |
| SCHEMBL30511704 | 0.83 | NCF1 (0.97) | NCF1ADRB2ADRB1HTTMAPK1 | |
| SCHEMBL900155 | 0.82 | NCF1 (0.82) | NCF1ADRB2ADRB1HTTMAPK1 | |
| SCHEMBL1366345 | 0.81 | NCF1 (0.75) | NCF1ADRB2ADRB1HTTMAPK1 | |
| SCHEMBL900149 | 0.81 | HTT (0.77) | NCF1ADRB2ADRB1HTTMAPK1 | |
| SCHEMBL21392990 | 0.80 | MEN1 (0.78) | NCF1ADRB2ADRB1HTTMAPK1 | |
| SCHEMBL8229816 | 0.80 | NCF1 (0.76) | NCF1ADRB2ADRB1HTTMAPK1 | |
| SCHEMBL17276464 | 0.80 | NCF1 (0.79) | NCF1ADRB2ADRB1HTTMAPK1 | |
| SCHEMBL30058841 | 0.80 | ADRB2 (0.68) | NCF1ADRB2HTTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235091-A1 | NOVEL HETEROCYCLIC COMPOUND AND USE THEREOF | 엠비디 주식회사 | 2022-11-10 | — | — | WO | claimed |
| WO-2022235091-A1 | NOVEL HETEROCYCLIC COMPOUND AND USE THEREOF | 엠비디 주식회사 | 2022-11-10 | — | — | WO | disclosed |
| WO-2021096335-A1 | NOVEL QUINOLINE COMPOUND AND USE THEREOF | 엠비디 주식회사 | 2021-05-20 | — | — | WO | disclosed |