Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.34 |
| ▸ | ITGAL | P20701 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.32 |
| ▸ | PDCD1LG2 | Q9BQ51 | 6/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10709560 | 0.82 | ITGB1 (0.39) | ITGB3ITGB2ITGB1ITGAVITGA2B | |
| SCHEMBL12027194 | 0.79 | IRAK4 (0.32) | MEN1KMT2AITGB3ITGB2ITGB1 | |
| SCHEMBL18289454 | 0.78 | ITGB1 (0.42) | MEN1GAAKMT2AITGB3ITGB2 | |
| SCHEMBL2558286 | 0.76 | ITGB1 (0.61) | MEN1GAAMAPTKMT2AITGB3 | |
| SCHEMBL9621834 | 0.76 | ITGB1 (0.61) | MEN1GAAMAPTKMT2AITGB3 | |
| SCHEMBL18705948 | 0.76 | ITGB1 (0.61) | MEN1GAAMAPTKMT2AITGB3 | |
| Methacrylic Acid SCHEMBL11888730 | 0.75 | ITGB1 (0.38) | ITGB3ITGB2ITGB1ITGAVITGA2B | |
| SCHEMBL10689544 | 0.74 | ITGB1 (0.39) | MEN1KMT2AITGB3ITGB2ITGB1 | |
| SCHEMBL21565414 | 0.74 | GAA (0.41) | GAAITGB3ITGB2ITGB1ITGAV | |
| SCHEMBL22259659 | 0.74 | ITGB1 (0.40) | MEN1KMT2AITGB3ITGB2ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023230542-A2 | PYRAZOLO[1,5-a]PYRIDINE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| WO-2021097116-A1 | NOVEL FUNCTIONALIZED LACTAMS AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-05-20 | — | — | WO | disclosed |