Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.61 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.61 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.61 |
| ▸ | ITGAV | P06756 | 1/20 | 0.61 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.61 |
| ▸ | ITGAL | P20701 | 1/20 | 0.61 |
| ▸ | SLC6A1 | P30531 | 4/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.43 |
| ▸ | SLC6A12 | P48065 | 4/20 | 0.43 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.43 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621834 | 1.00 | ITGB1 (0.61) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL18705948 | 1.00 | ITGB1 (0.61) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL11665810 | 0.88 | ITGB3 (0.57) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL6797323 | 0.86 | ITGB1 (0.55) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL18289454 | 0.85 | ITGB1 (0.42) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL10689544 | 0.82 | ITGB1 (0.39) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL10709560 | 0.82 | ITGB1 (0.39) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL31124620 | 0.80 | ITGB1 (0.42) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL31124633 | 0.80 | ITGB1 (0.42) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL4579585 | 0.80 | ITGB1 (0.42) | ITGB1ITGA5ITGB3ITGA2BITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114249678-A | Preparation method of N- (aminothiomethyl) -5-oxo-1-propyl-2-pyrrolidine acetamide | 深圳翰宇药业股份有限公司 | 2022-03-29 | — | — | CN | claimed |
| JP-52118463-A | — | — | None | — | — | JP | disclosed |
| JP-52053854-A | — | — | None | — | — | JP | disclosed |
| JP-52133969-A | — | — | None | — | — | JP | disclosed |
| EP-4251615-B1 | SPIRO[3.3]HEPTANE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2025-10-15 | — | — | EP | disclosed |
| EP-4631573-A2 | TEAD INHIBITORS | Orion Corporation (FI) | 2025-10-15 | — | — | EP | disclosed |
| EP-4323338-B1 | TEAD INHIBITORS | ORION CORP (FI) | 2025-10-08 | — | — | EP | disclosed |
| WO-2025034613-A1 | 3H-IMIDAZO[4,5-B]PYRIDINE COMPOUNDS AS NON-COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2025-02-13 | — | — | WO | disclosed |
| US-20240246908-A1 | TEAD INHIBITORS | ORION CORPORATION (FI) | 2024-07-25 | — | — | US | disclosed |
| WO-2024081762-A1 | SUBSTITUTED 5-MEMBERED RINGS AND THEIR USE AS PESTICIDES | CORTEVA AGRISCIENCE LLC (US) | 2024-04-18 | — | — | WO | disclosed |
| US-5175158-A | CONDENSED DIAZEPINONES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | DR. KARL THOMAE, GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| US-5110823-A | Cognition activators | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-05-05 | — | — | US | disclosed |
| EP-0306698-B1 | CONDENSED DIAZEPINONES, PROCESSES FOR THEIR PREPARATION, AND MEDICAMENTS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1992-03-25 | — | — | EP | disclosed |
| US-4931436-A | BRADYCARDIAL AGENTS | DR. KARL THOMAE GMBH (DE) | 1990-06-05 | — | — | US | disclosed |
| EP-0174136-B1 | DERIVATIVES OF DIHYDRO-1H-PYRROLO(1,2-C)IMIDAZOL-3,5-DIONE AS COGNITION ACTIVATORS | WARNER-LAMBERT COMPANY (US) | 1989-03-22 | — | — | EP | disclosed |
| US-4582838-A | FOR TREATING SENILITY OR REVERSING EFFECTS OF ELECTROCONVULSIVE SHOCK-INDUCED AMNESIA | WARNER-LAMBERT COMPANY (US) | 1986-04-15 | — | — | US | disclosed |
| EP-0174136-A1 | Derivatives of dihydro-1H-pyrrolo(1,2-c)imidazol-3,5-dione as cognition activators | WARNER-LAMBERT COMPANY (US) | 1986-03-12 | — | — | EP | disclosed |
| JP-S52133969-A | SYNTHESIS OF OPTICALLY ACTIVE LACTAM | TEIJIN LTD | 1977-11-09 | — | — | JP | disclosed |
| JP-S52118463-A | SYNTHESIS OF HOMOPROLINE | TEIJIN LTD | 1977-10-04 | — | — | JP | disclosed |
| JP-S5253854-A | PREPARING OPTICAL ACTIVE PYPROLIDINE ETHANOLS | TEIJIN LTD | 1977-04-30 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246908-A1 | TEAD INHIBITORS | TEAD3, TEAD1, TEAD2 | ITGB1 3683/4885ITGA5 3339/4885ITGB3 2938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.