Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.61 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.61 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.61 |
| ▸ | ITGAV | P06756 | 1/20 | 0.61 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.61 |
| ▸ | ITGAL | P20701 | 1/20 | 0.61 |
| ▸ | SLC6A1 | P30531 | 4/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.43 |
| ▸ | SLC6A12 | P48065 | 4/20 | 0.43 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.43 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558286 | 1.00 | ITGB1 (0.61) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL18705948 | 1.00 | ITGB1 (0.61) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL11665810 | 0.88 | ITGB3 (0.57) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL6797323 | 0.86 | ITGB1 (0.55) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL18289454 | 0.85 | ITGB1 (0.42) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL10689544 | 0.82 | ITGB1 (0.39) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL10709560 | 0.82 | ITGB1 (0.39) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL31124620 | 0.80 | ITGB1 (0.42) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL31124633 | 0.80 | ITGB1 (0.42) | ITGB1ITGA5ITGB3ITGA2BITGB2 | |
| SCHEMBL4579585 | 0.80 | ITGB1 (0.42) | ITGB1ITGA5ITGB3ITGA2BITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025217020-A1 | SUBSTITUTED 5-MEMBERED RING MOLECULES AND THEIR USE AS PESTICIDES | CORTEVA AGRISCIENCE LLC (US) | 2025-10-16 | — | — | WO | disclosed |
| WO-2024081762-A1 | SUBSTITUTED 5-MEMBERED RINGS AND THEIR USE AS PESTICIDES | CORTEVA AGRISCIENCE LLC (US) | 2024-04-18 | — | — | WO | disclosed |
| US-20230002383-A1 | NOVEL FUNCTIONALIZED LACTAMS AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE | PRAEVENTIX, LLC | 2023-01-05 | — | — | US | disclosed |
| EP-4058455-A1 | NOVEL FUNCTIONALIZED LACTAMS AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE | Temple University - Of The Commonwealth System of Higher Education (US) | 2022-09-21 | — | — | EP | disclosed |
| CN-115003675-A | Novel functionalized lactams as 5-hydroxytryptamine receptor 7 modulators and methods of use thereof | 英联邦高等教育系统坦普尔大学 | 2022-09-02 | — | — | CN | disclosed |
| WO-2021097116-A1 | NOVEL FUNCTIONALIZED LACTAMS AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-05-20 | — | — | WO | disclosed |
| EP-3790859-A1 | NOVEL FUNCTIONALIZED LACTAMS AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE | Temple University - Of The Commonwealth System of Higher Education (US) | 2021-03-17 | — | — | EP | disclosed |
| CN-112437768-A | Novel functionalized lactams as 5-hydroxytryptamine receptor 7 modulators and methods of use thereof | 英联邦高等教育系统坦普尔大学 | 2021-03-02 | — | — | CN | disclosed |
| WO-2019217890-A1 | NOVEL FUNCTIONALIZED LACTAMS AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2019-11-14 | — | — | WO | disclosed |
| WO-2013041899-A1 | FOLDAMERS CONTAINING CYCLIC GAMMA AMINO ACID RESIDUES, EVENTUALLY ALTERNATING WITH ALPHA- AMINOISOBUTYRIC ACID | UNIVERSITE PARIS-SUD XI (FR) | 2013-03-28 | — | — | WO | disclosed |
| US-5110823-A | Cognition activators | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002383-A1 | NOVEL FUNCTIONALIZED LACTAMS AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE | HTR7, HTR1A, HTR2C | ITGB1 2838/4885ITGA5 1494/4885ITGB3 1645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.