Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.75 |
| ▸ | RAB9A | P51151 | 9/20 | 0.75 |
| ▸ | MAPT | P10636 | 8/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.75 |
| ▸ | TP53 | P04637 | 7/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.75 |
| ▸ | MEN1 | O00255 | 5/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.75 |
| ▸ | HPGD | P15428 | 5/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.75 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.75 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.75 |
| ▸ | RELA | Q04206 | 2/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2247122 | 0.86 | RAB9A (1.00) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL11310904 | 0.86 | NPC1 (0.74) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL19806580 | 0.85 | MAPT (0.85) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL19380022 | 0.83 | MAPT (0.79) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL10289630 | 0.82 | SMN1; SMN2 (0.74) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL23373921 | 0.82 | NPC1 (0.69) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL29859231 | 0.82 | MAPT (0.54) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL23630624 | 0.82 | MAPT (0.54) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL1024854 | 0.81 | ALDH1A1 (0.72) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL23373978 | 0.81 | NPC1 (0.68) | NPC1RAB9AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746254-B2 | Tunable refractive index polymers | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2023-09-05 | — | — | US | disclosed |
| US-20210147707-A1 | TUNABLE REFRACTIVE INDEX POLYMERS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2021-05-20 | — | — | US | disclosed |