SCHEMBL233743

SCHEMBL233743

CCOC(=O)C1(C(=O)OCC)CCC(C)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.38
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
LMNA P02545 2/20 0.36
POLB P06746 1/20 0.36
ALDH1A1 P00352 2/20 0.36
TP53 P04637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
OPRM1 P35372 3/20 0.35
HSD17B10 Q99714 1/20 0.34
OPRD1 P41143 2/20 0.34
OPRK1 P41145 2/20 0.34
ATM Q13315 1/20 0.34
SLC22A1 O15245 1/20 0.34
SLC6A4 P31645 1/20 0.34
ADRA1A P35348 1/20 0.34
KCNH2 Q12809 1/20 0.34
PKM P14618 1/20 0.34
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6745756 0.84 POLB (0.36) SMN1; SMN2MEN1KMT2ALMNAPOLB
SCHEMBL18134201 0.83 ALDH1A1 (0.46) KDM4ESMN1; SMN2MEN1KMT2ALMNA
SCHEMBL69496 0.83 ALDH1A1 (0.46) KDM4ESMN1; SMN2MEN1KMT2ALMNA
SCHEMBL18082673 0.82 KDM4E (0.40) KDM4ESMN1; SMN2MEN1KMT2ALMNA
SCHEMBL7409982 0.82 SMYD3 (0.40) SMN1; SMN2LMNAPOLBALDH1A1OPRM1
SCHEMBL1908605 0.82 KDM4E (0.40) KDM4ESMN1; SMN2MEN1KMT2ALMNA
SCHEMBL22639506 0.79 FPR2 (0.34) SMN1; SMN2MEN1KMT2ALMNAPOLB
SCHEMBL18849597 0.79 KDM4E (0.39) KDM4ESMN1; SMN2MEN1KMT2ALMNA
SCHEMBL12030067 0.79 ALDH1A1 (0.39) KDM4ESMN1; SMN2MEN1KMT2ALMNA
SCHEMBL713102 0.79 SMN1; SMN2 (0.46) SMN1; SMN2MEN1KMT2ALMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
EP-2636688-A1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND OLEFIN POLYMERS Toho Titanium Co., Ltd. (JP) 2013-09-11 EP disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed