SCHEMBL23375474

SCHEMBL23375474

C=CCNC(=S)Nc1ccccc1F

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.68
KMT2A Q03164 4/20 0.64
MEN1 O00255 3/20 0.64
L3MBTL1 Q9Y468 1/20 0.59
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
CYP1A2 P05177 1/20 0.57
CYP3A4 P08684 1/20 0.57
CYP2D6 P10635 1/20 0.57
CYP2C9 P11712 1/20 0.57
CYP2C19 P33261 1/20 0.57
MAPT P10636 2/20 0.53
ALDH1A1 P00352 1/20 0.53
POLB P06746 2/20 0.52
GAA P10253 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5463769 0.81 MEN1 (0.64) LMNAKMT2AMEN1L3MBTL1SMN1; SMN2
SCHEMBL5449341 0.78 ALDH1A1 (0.70) LMNAKMT2AMEN1L3MBTL1NPC1
SCHEMBL29838503 0.78 ALDH1A1 (0.70) LMNAKMT2AMEN1L3MBTL1NPC1
SCHEMBL3065751 0.78 KMT2A (1.00) LMNAKMT2AMEN1SMN1; SMN2MAPT
SCHEMBL5450015 0.78 ALDH1A1 (0.73) LMNAKMT2AMEN1L3MBTL1NPC1
SCHEMBL1647857 0.78 ALDH1A1 (0.69) LMNAKMT2AMEN1NPC1RAB9A
SCHEMBL29000353 0.77 KMT2A (0.59) LMNAKMT2AMEN1MAPTALDH1A1
SCHEMBL28820782 0.77 KMT2A (0.64) LMNAKMT2AMEN1RAB9ASMN1; SMN2
SCHEMBL11803606 0.77 NPC1 (0.69) LMNAKMT2AMEN1L3MBTL1NPC1
SCHEMBL5450433 0.76 KMT2A (0.58) LMNAKMT2AMEN1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260128361-A1 FUNCTIONAL ALIPHATIC AND/OR AROMATIC AMINE COMPOUNDS OR DERIVATIVES AS ELECTROLYTE ADDITIVES TO REDUCE GAS GENERATION IN LI-ION BATTERIES ENEVATE CORP (US) 2026-05-07 US disclosed
US-12438181-B2 Functional aliphatic and/or aromatic amine compounds or derivatives as electrolyte additives to reduce gas generation in Li-ion batteries ENEVATE CORPORATION (US) 2025-10-07 US disclosed
US-20210328256-A1 FUNCTIONAL ALIPHATIC AND/OR AROMATIC AMINE COMPOUNDS OR DERIVATIVES AS ELECTROLYTE ADDITIVES TO REDUCE GAS GENERATION IN LI-ION BATTERIES ENEVATE CORPORATION 2021-10-21 US disclosed
US-20210328256-A1 FUNCTIONAL ALIPHATIC AND/OR AROMATIC AMINE COMPOUNDS OR DERIVATIVES AS ELECTROLYTE ADDITIVES TO REDUCE GAS GENERATION IN LI-ION BATTERIES ENEVATE CORPORATION 2021-10-21 US disclosed
WO-2021194742-A1 FUNCTIONAL ALIPHATIC AND/OR AROMATIC AMINE COMPOUNDS OR DERIVATIVES AS ELECTROLYTE ADDITIVES TO REDUCE GAS GENERATION IN LI-ION BATTERIES ENEVATE CORPORATION (US) 2021-09-30 WO disclosed
WO-2021194742-A1 FUNCTIONAL ALIPHATIC AND/OR AROMATIC AMINE COMPOUNDS OR DERIVATIVES AS ELECTROLYTE ADDITIVES TO REDUCE GAS GENERATION IN LI-ION BATTERIES ENEVATE CORPORATION (US) 2021-09-30 WO disclosed
US-11018371-B1 Functional aliphatic and/or aromatic amine compounds or derivatives as electrolyte additives to reduce gas generation in li-ion batteries ENEVATE CORPORATION (US) 2021-05-25 US disclosed
US-11018371-B1 Functional aliphatic and/or aromatic amine compounds or derivatives as electrolyte additives to reduce gas generation in li-ion batteries ENEVATE CORPORATION (US) 2021-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260128361-A1 FUNCTIONAL ALIPHATIC AND/OR AROMATIC AMINE COMPOUNDS OR DERIVATIVES AS ELECTROLYTE ADDITIVES TO REDUCE GAS GENERATION IN LI-ION BATTERIES LAGE3, ROS1, CACNA2D3 LMNA 1254/4885KMT2A 811/4885MEN1 4270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.