SCHEMBL23375982

SCHEMBL23375982

CC1(C)c2ccccc2-c2cc(N(c3ccc(-c4cccc5oc6ccccc6c45)cc3)c3ccc4c(c3)C(C)(C)c3ccccc3-4)ccc21

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TNKS O95271 1/20 0.32
ALK Q9UM73 4/20 0.31
BACE1 P56817 1/20 0.30
PDK2 Q15119 1/20 0.30
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23376295 0.97 TNKS (0.33) TNKSALKBACE1ALOX5
SCHEMBL25814163 0.96 ALK (0.32) TNKSALK
SCHEMBL25813462 0.96 ALK (0.32) TNKSALK
SCHEMBL25813537 0.94 ALK (0.31) ALK
SCHEMBL20806541 0.94 TNKS (0.31) TNKSALK
SCHEMBL24255763 0.94 TNKS (0.32) TNKSALKBACE1PDK2ALOX5
SCHEMBL17721411 0.94 TNKS (0.32) TNKSALKBACE1PDK2ALOX5
SCHEMBL25813679 0.93 PDK2 (0.33) ALKPDK2
SCHEMBL25814239 0.93 ALK (0.31) ALK
SCHEMBL25878341 0.93 TNKS (0.30) TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210147375-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210147375-A1 MATERIALS FOR ELECTRONIC DEVICES PNMT, EFNA1, TES TNKS 1443/4885ALK 1411/4885BACE1 4075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.