Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2521102 | 0.91 | TSHR (0.44) | TSHRRAB9ANPC1CYP2C9ALDH1A1 | |
| SCHEMBL2331140 | 0.90 | TSHR (0.45) | TSHRRAB9ANPC1CYP2C9ALDH1A1 | |
| SCHEMBL2520455 | 0.89 | TSHR (0.43) | TSHRRAB9ACYP2C9ALDH1A1KDM4E | |
| SCHEMBL2523583 | 0.87 | TSHR (0.43) | TSHRRAB9ANPC1CYP2C9ALDH1A1 | |
| SCHEMBL2520436 | 0.85 | TSHR (0.45) | TSHRRAB9ANPC1CYP2C9ALDH1A1 | |
| SCHEMBL2520591 | 0.84 | CYP2A6 (0.41) | TSHRCYP2C9KDM4ECYP2D6CYP2C19 | |
| SCHEMBL2334999 | 0.83 | TSHR (0.43) | TSHRRAB9ACYP2C9ALDH1A1KDM4E | |
| SCHEMBL2520440 | 0.83 | TSHR (0.43) | TSHRRAB9ACYP2C9ALDH1A1KDM4E | |
| SCHEMBL2522127 | 0.81 | TSHR (0.41) | TSHRRAB9ACYP2C9CYP1A2CYP2D6 | |
| SCHEMBL2332017 | 0.81 | TSHR (0.45) | TSHRRAB9ANPC1CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110251069-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-13 | — | — | US | disclosed |
| US-20110251069-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-13 | — | — | US | disclosed |
| US-20110251069-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-13 | — | — | US | disclosed |
| EP-2358201-A2 | THIOPHENE, FURAN AND PYRROLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | Syngenta Participations AG (CH) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010069880-A2 | THIOPHENE, FURAN AND PYRROLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-24 | — | — | WO | disclosed |
| US-20070244162-A1 | SUBSTITUTED AROMATIC HETEROCYCLIC COMPOUNDS AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2007-10-18 | — | — | US | disclosed |
| US-20070244162-A1 | SUBSTITUTED AROMATIC HETEROCYCLIC COMPOUNDS AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2007-10-18 | — | — | US | disclosed |
| US-20070244162-A1 | SUBSTITUTED AROMATIC HETEROCYCLIC COMPOUNDS AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244162-A1 | SUBSTITUTED AROMATIC HETEROCYCLIC COMPOUNDS AS FUNGICIDES | NOX5, CYP3A5, API5 | TSHR 2380/4885RAB9A 2392/4885NPC1 2117/4885 |
| US-20110251069-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | FKBP5, FKBP2, FKBP1B | TSHR 556/4885RAB9A 3650/4885NPC1 4765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.