SCHEMBL23389869

SCHEMBL23389869

C=C(C)C(=O)OC(=O)/C=C/c1ccc(O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.60
CA7 P43166 6/20 0.60
CA9 Q16790 6/20 0.60
CA14 Q9ULX7 6/20 0.60
CA1 P00915 5/20 0.60
CA2 P00918 4/20 0.60
TYR P14679 3/20 0.60
AKR1B10 O60218 5/20 0.55
AKR1B1 P15121 5/20 0.55
F3 P13726 3/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
HSD11B1 P28845 1/20 0.50
CA4 P22748 3/20 0.49
CA6 P23280 3/20 0.49
CA5A P35218 3/20 0.49
CA5B Q9Y2D0 3/20 0.49
ESR1 P03372 1/20 0.49
CA3 P07451 1/20 0.49
PKM P14618 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10760753 0.85 GLA (0.55) AKR1B10AKR1B1F3CYP2D6CYP2C9
SCHEMBL4122409 0.85 GLA (0.55) AKR1B10AKR1B1F3CYP2D6CYP2C9
SCHEMBL14300981 0.83 CA12 (0.55) CA12CA7CA9CA14CA1
SCHEMBL29397395 0.83 APP (0.63) CA12CA7CA9CA14CA1
SCHEMBL11095177 0.83 CA12 (0.68) CA12CA7CA9CA14CA1
SCHEMBL10891552 0.82 CA12 (0.71) CA12CA7CA9CA14CA1
SCHEMBL3314742 0.82 CA12 (0.71) CA12CA7CA9CA14CA1
SCHEMBL4578918 0.82 CA12 (0.65) CA12CA7CA9CA14CA1
SCHEMBL6389147 0.82 CA12 (0.65) CA12CA7CA9CA14CA1
SCHEMBL6536636 0.81 CA12 (0.64) CA12CA7CA9CA14CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021097531-A1 POLYIONIC CORROSION INHIBITORS DEAKIN UNIVERSITY (AU) 2021-05-27 WO disclosed