Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 3/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dacarbazine SCHEMBL1586950 | 0.79 | PAX8 (0.59) | KDM4ELMNATSHRALDH1A1PAX8 | |
| Dacarbazine SCHEMBL12591753 | 0.79 | PAX8 (0.59) | KDM4ELMNATSHRALDH1A1PAX8 | |
| Dacarbazine SCHEMBL5560 | 0.79 | PAX8 (0.59) | KDM4ELMNATSHRALDH1A1PAX8 | |
| Dacarbazine SCHEMBL6372 | 0.79 | PAX8 (0.59) | KDM4ELMNATSHRALDH1A1PAX8 | |
| Dacarbazine SCHEMBL28074490 | 0.78 | PAX8 (0.57) | KDM4ELMNATSHRALDH1A1PAX8 | |
| Dacarbazine SCHEMBL28090781 | 0.78 | PAX8 (0.57) | KDM4ELMNATSHRALDH1A1PAX8 | |
| Dacarbazine SCHEMBL28074492 | 0.78 | PAX8 (0.57) | KDM4ELMNATSHRALDH1A1PAX8 | |
| Dacarbazine SCHEMBL3957404 | 0.78 | PAX8 (0.57) | KDM4ELMNATSHRALDH1A1PAX8 | |
| Dacarbazine SCHEMBL28090782 | 0.78 | PAX8 (0.57) | KDM4ELMNATSHRALDH1A1PAX8 | |
| Dacarbazine SCHEMBL28242658 | 0.78 | PAX8 (0.57) | KDM4ELMNATSHRALDH1A1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014953-B2 | Trigger-activatable metabolic sugar precursors for cancer-selective labeling and targeting | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11014953-B2 | Trigger-activatable metabolic sugar precursors for cancer-selective labeling and targeting | GPI, SLC2A1, SLC2A4 | KDM4E 1494/4885LMNA 3922/4885TSHR 1316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.