SCHEMBL233947

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL236851	0.89	TAAR1 (0.42)	TAAR1MAP3K14GRM5LTA4HPLA2G2A
	SCHEMBL232951	0.89	TAAR1 (0.42)	TAAR1MAP3K14GRM5LTA4HPLA2G2A
	SCHEMBL234371	0.88	TAAR1 (0.41)	TAAR1MAP3K14GRM5LTA4HPLA2G2A
	SCHEMBL235944	0.88	TAAR1 (0.41)	TAAR1MAP3K14GRM5LTA4HPLA2G2A
	SCHEMBL232824	0.88	TAAR1 (0.41)	TAAR1MAP3K14GRM5LTA4HPLA2G2A
	SCHEMBL234441	0.85	TAAR1 (0.40)	TAAR1MAP3K14GRM5LTA4HPLA2G2A
	SCHEMBL237406	0.77	HPGD (0.36)	TAAR1MAP3K14GRM5RIPK1HPGD
	SCHEMBL20724260	0.76	ALOX5 (0.47)	ALOX5MAP3K14GRM5RIPK1
	SCHEMBL14643012	0.76	HRH3 (0.44)	TAAR1ALOX5PDK2HRH3
	SCHEMBL232756	0.72	TAAR1 (0.66)	TAAR1LTA4HPLA2G2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.