Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | P4HB | P07237 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102981 | 0.79 | CA12 (0.64) | HDAC2ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL7102972 | 0.79 | CA12 (0.64) | HDAC2ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL1910479 | 0.77 | ALDH1A1 (0.48) | HDAC2ALDH1A1MAPTLMNAGAA | |
| SCHEMBL13177035 | 0.76 | ALDH1A1 (0.51) | HDAC2ALDH1A1MAPTLMNAMAOB | |
| SCHEMBL13114501 | 0.76 | HDAC2 (0.68) | HDAC2ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL10995556 | 0.74 | GSK3B (0.55) | HDAC2ALDH1A1MAPTLMNAL3MBTL1 | |
| Oxirane SCHEMBL28643072 | 0.73 | CA12 (0.55) | HDAC2ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL1342975 | 0.73 | MAPT (0.60) | HDAC2ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL1342977 | 0.73 | MAPT (0.60) | HDAC2ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL20244293 | 0.72 | MAPT (0.69) | HDAC2ALDH1A1MAPTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3825409-A1 | COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2021-05-26 | — | — | EP | disclosed |
| US-9533974-B2 | Ultra-sensitive chemiluminescent substrates for enzymes and their conjugates | MICHIGAN DIAGNOSTICS, LLC (US) | 2017-01-03 | — | — | US | disclosed |