SCHEMBL7102972

SCHEMBL7102972

COC(=O)/C=C/c1ccc(C#N)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.64
CA1 P00915 2/20 0.64
CA2 P00918 2/20 0.64
CA9 Q16790 2/20 0.64
TYR P14679 1/20 0.64
CA7 P43166 1/20 0.64
CA14 Q9ULX7 1/20 0.64
HDAC2 Q92769 2/20 0.59
MAPT P10636 4/20 0.55
ALDH1A1 P00352 4/20 0.55
LMNA P02545 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
PTPN1 P18031 1/20 0.55
TTR P02766 1/20 0.54
APP P05067 1/20 0.54
P4HB P07237 1/20 0.54
HTT P42858 2/20 0.50
EPHX2 P34913 1/20 0.50
SNCA P37840 2/20 0.49
KDM4E B2RXH2 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7102981 1.00 CA12 (0.64) CA12CA1CA2CA9TYR
SCHEMBL13114501 0.95 HDAC2 (0.68) CA12CA1CA2CA9TYR
Oxirane SCHEMBL28643072 0.92 CA12 (0.55) CA12CA1CA2CA9TYR
SCHEMBL7272534 0.85 HDAC2 (0.49) CA12CA1CA2CA9TYR
SCHEMBL7272529 0.85 HDAC2 (0.49) CA12CA1CA2CA9TYR
SCHEMBL71224 0.85 CA12 (0.84) CA12CA1CA2CA9TYR
SCHEMBL5057418 0.85 CA12 (0.84) CA12CA1CA2CA9TYR
SCHEMBL7283113 0.84 HDAC2 (0.48) CA12CA1CA2CA9TYR
SCHEMBL7283110 0.84 HDAC2 (0.48) CA12CA1CA2CA9TYR
SCHEMBL7368327 0.84 P4HB (0.52) CA12CA1CA2CA9TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119708027-A Method for preparing boronated carbonyl derivative 中国科学院大连化学物理研究所 2025-03-28 CN claimed
EP-3208301-B1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME TOSOH CORP (JP) 2019-04-03 EP claimed
US-10126478-B2 Resin composition and optical compensation film using same TOSOH CORPORATION (JP) 2018-11-13 US claimed
US-20170242174-A1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME TOSOH CORPORATION (JP) 2017-08-24 US claimed
EP-3208301-A1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME Tosoh Corporation (JP) 2017-08-23 EP claimed
US-11518938-B2 Optical film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2022-12-06 US disclosed
US-20220315686-A1 CURABLE COMPOSITION, CURED SUBSTANCE, OPTICAL MEMBER, AND LENS FUJIFILM CORPORATION (JP) 2022-10-06 US disclosed
WO-2021132037-A1 CURABLE COMPOSITION, CURED PRODUCT, OPTICAL MEMBER AND LENS 富士フイルム株式会社 2021-07-01 WO disclosed
US-20200399538-A1 OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2020-12-24 US disclosed
US-10620481-B2 Optical alignment film composition, optical alignment film, optical laminate, and image display device FUJIFILM CORPORATION (JP) 2020-04-14 US disclosed
EP-3208301-B1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME TOSOH CORP (JP) 2019-04-03 EP disclosed
US-10126478-B2 Resin composition and optical compensation film using same TOSOH CORPORATION (JP) 2018-11-13 US disclosed
WO-1995023609-A1 ANTITHROMBOTIC AGENTS ELI LILLY AND COMPANY (US) 1995-09-08 WO disclosed
US-5231102-A Tetrahydroquinoline derivatives useful for neurodegenerative disorders MERCK SHARP & DOHME, LTD. (GB) 1993-07-27 US disclosed
US-5216158-A Oxadiazole compounds containing 4,6-bis-trichloromethyl-S-triazin-2-yl groups, process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-01 US disclosed
US-5064959-A Photoinitiators HOECHST AKTIENGESELLSCHAFT (DE) 1991-11-12 US disclosed
EP-0386839-A2 Tetrahydroquinoline derivatives useful for neurodegenerative disorders MERCK SHARP & DOHME LTD. (GB) 1990-09-12 EP disclosed
EP-0153720-B1 SPERGUALIN-RELATED COMPOUNDS HAVING A PHENYLENE GROUP, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1988-11-09 EP disclosed
US-4556735-A BACTERICIDE, ANTITUMOR AGENT ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYUKAI (JP) 1985-12-03 US disclosed
EP-0153720-A2 Spergualin-related compounds having a phenylene group, a process for their preparation and their use as medicaments MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1985-09-04 EP disclosed