SCHEMBL233963

SCHEMBL233963

CN(C)C1(O)CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 7/20 0.33
SLC6A4 P31645 7/20 0.33
SLC6A3 Q01959 4/20 0.33
ALDH1A1 P00352 1/20 0.33
OPRM1 P35372 1/20 0.33
LMNA P02545 2/20 0.31
GAA P10253 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9802008 1.00 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3ALDH1A1OPRM1
SCHEMBL8316585 0.97
SCHEMBL31058313 0.90
SCHEMBL28821044 0.75 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3ALDH1A1OPRM1
SCHEMBL28414632 0.73 ALDH1A1 (0.36) ALDH1A1
SCHEMBL305703 0.73 ALDH1A1 (0.36) ALDH1A1
SCHEMBL27433030 0.71 TAS2R38 (0.30)
SCHEMBL6823771 0.71 MEN1 (0.33) ALDH1A1
SCHEMBL5417347 0.69
SCHEMBL9801157 0.69 SLC6A2 (0.31) SLC6A2SLC6A4SLC6A3OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023168218-A2 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC COPOLYMERIZATION OF CONJUGATED DIENES AND LIQUID COPOLYMERS THEREOF ALBEMARLE CORPORATION (US) 2023-09-07 WO claimed
EP-4208485-A1 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC POLYMERIZATION OF CONJUGATED DIENES AND LIQUID POLYMERS THEREOF ALBEMARLE CORPORATION (US) 2023-07-12 EP claimed
CN-115554812-A Accelerant and absorbent for carbon dioxide absorbent and method for reducing carbon dioxide emission 中国石油化工股份有限公司 2023-01-03 CN claimed
CN-110227161-A CNS inhibitor is combined with opioid for the purposes in endoscopy 江苏恒瑞医药股份有限公司 2019-09-13 CN claimed
US-9562014-B2 (+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof MALLINCKRODT LLC (US) 2017-02-07 US claimed
US-20170029432-A1 (+)-MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF MALLINCKRODT ENTERPRISES LLC 2017-02-02 US claimed
EP-2593095-A1 (+)-MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF Mallinckrodt LLC (US) 2013-05-22 EP claimed
CN-102766247-A Rigid polyurethane/polyvinyl chloride composite foam plastic and preparation method thereof SHANGHAI CHLOR ALKALI CHEMICAL 2012-11-07 CN claimed
EP-2059333-B1 AMINE AQUEOUS SOLUTION FOR FORMING AN ACTIVE LAYER OF POLYAMIDE REVERSE OSMOSIS COMPOSITE MEMBRANE AND PREPARATION METHOD OF POLYAMIDE REVERSE OSMOSIS COMPOSITE MEMBRANE USING THE SAME WOONGJINCOWAY CO LTD (KR) 2012-10-31 EP claimed
CN-101511459-B Amine aqueous solution for forming an active layer of polyamide reverse osmosis composite membrane, polyamide reverse osmosis composite membrane prepared thereby, and preparation method thereof WOONGJIN COWAY CO LTD 2012-08-08 CN claimed
WO-2012008984-A1 (+)-MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF MALLINCKRODT LLC (US) 2012-01-19 WO claimed
US-20120003387-A1 AMINE AQUEOUS SOLUTION FOR FORMING AN ACTIVE LAYER OF POLYAMIDE REVERSE OSMOSIS COMPOSITE MEMBRANE, POLYAMIDE REVERSE OSMOSIS COMPOSITE MEMBRANE PREPARED THEREBY, AND PREPARATION METHOD THEREOF KIM YOUN-KOOK (KR) 2012-01-05 US claimed
JP-4827968-B2 2011-11-30 JP claimed
US-20110136845-A1 (+)-Morphinans as Antagonists of Toll-Like Receptor 9 and Therapeutic Uses Thereof MALLINCKRODT INC. (US) 2011-06-09 US claimed
US-20100181250-A1 AMINE AQUEOUS SOLUTION FOR FORMING AN ACTIVE LAYER OF POLYAMIDE REVERSE OSMOSIS COMPOSITE MEMBRANE, POLYAMIDE REVERSE OSMOSIS COMPOSITE MEMBRANE PREPARED THEREBY, AND PREPARATION METHOD THEREOF WOONGJINCOWAY CO., LTD. (KR) 2010-07-22 US claimed
CN-101511459-A Amine aqueous solution for forming an active layer of polyamide reverse osmosis composite membrane, polyamide reverse osmosis composite membrane prepared thereby, and preparation method thereof WOONGJIN COWAY CO LTD (KR) 2009-08-19 CN claimed
EP-2059333-A1 AMINE AQUEOUS SOLUTION FOR FORMING AN ACTIVE LAYER OF POLYAMIDE REVERSE OSMOSIS COMPOSITE MEMBRANE, POLYAMIDE REVERSE OSMOSIS COMPOSITE MEMBRANE PREPARED THEREBY, AND PREPARATION METHOD THEREOF Woongjincoway Co, Ltd. (KR) 2009-05-20 EP claimed
WO-2008030006-A1 AMINE AQUEOUS SOLUTION FOR FORMING AN ACTIVE LAYER OF POLYAMIDE REVERSE OSMOSIS COMPOSITE MEMBRANE, POLYAMIDE REVERSE OSMOSIS COMPOSITE MEMBRANE PREPARED THEREBY, AND PREPARATION METHOD THEREOF WOONGJINCOWAY CO, LTD, . (KR) 2008-03-13 WO claimed
CN-115554812-A Accelerant and absorbent for carbon dioxide absorbent and method for reducing carbon dioxide emission 中国石油化工股份有限公司 2023-01-03 CN disclosed
US-4239504-A Free base amino alcohols as electrostatic precipitator efficiency enhancers BETZ LABORATORIES, INC. (US) 1980-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170029432-A1 (+)-MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF TLR9, TLR3, TLR7 SLC6A2 87/4885SLC6A4 83/4885SLC6A3 134/4885
US-20110136845-A1 (+)-Morphinans as Antagonists of Toll-Like Receptor 9 and Therapeutic Uses Thereof TLR9, TLR3, TLR7 SLC6A2 87/4885SLC6A4 83/4885SLC6A3 134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.