Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR39 | O43194 | 2/20 | 0.40 |
| ▸ | PFKFB3 | Q16875 | 6/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | USP1 | O94782 | 1/20 | 0.34 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | TPH1 | P17752 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23396818 | 0.89 | HDAC1 (0.44) | GPR39PTGDRAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL23396787 | 0.87 | CYP1A2 (0.48) | TP53ALDH1A1CYP1A2CYP2D6HSD17B10 | |
| SCHEMBL23396899 | 0.87 | HDAC1 (0.37) | PTGDRAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL23396830 | 0.83 | AAK1 (0.41) | TP53ALDH1A1CYP1A2CYP2D6HSD17B10 | |
| SCHEMBL23396976 | 0.83 | DYRK1A (0.43) | CLK4HDAC8HDAC1 | |
| SCHEMBL23396862 | 0.83 | CYP1A2 (0.48) | TP53ALDH1A1CYP1A2CYP2D6HSD17B10 | |
| SCHEMBL23397023 | 0.82 | HDAC6 (0.35) | AKR1C4AKR1C3AKR1C2AKR1C1ALDH1A1 | |
| SCHEMBL23397038 | 0.80 | TPH1 (0.40) | AKR1C4AKR1C3AKR1C2AKR1C1VCP | |
| SCHEMBL23397070 | 0.80 | INSR (0.37) | AKR1C4AKR1C3AKR1C2AKR1C1HDAC1 | |
| SCHEMBL23397083 | 0.79 | CYP1A2 (0.35) | AKR1C4AKR1C3AKR1C2AKR1C1VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3359154-B1 | WNT SIGNALING PATHWAY INHIBITORS AND THERAPEUTIC APPLICATIONS THEREOF | Suzhou Yunxuan Yiyao Keji Youxian Gongsi (CN) | 2021-05-26 | — | — | EP | disclosed |