Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 8/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23398242 | 0.84 | KDM4E (0.36) | KDM4EL3MBTL1MAPTATMMEN1 | |
| SCHEMBL17224757 | 0.78 | NQO1 (0.42) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17224792 | 0.75 | MAPT (0.39) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17224760 | 0.69 | KMT2A (0.35) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17224759 | 0.69 | ALDH1A1 (0.37) | KDM4ERAB9AALDH1A1PKMHPGD | |
| SCHEMBL17224777 | 0.68 | ALDH1A1 (0.38) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL17224787 | 0.68 | NQO1 (0.41) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17224771 | 0.68 | MAPK8 (0.43) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30576370 | 0.68 | MAPK8 (0.43) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17224793 | 0.68 | KDM4E (0.42) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137456-B1 | PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-06-02 | — | — | EP | claimed |