Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL945107 | 0.85 | BCHE (0.71) | BCHEPTGS2ALOX15ALDH1A1LMNA | |
| SCHEMBL23402694 | 0.83 | BCHE (0.74) | BCHEPTGS2ALOX15ALDH1A1LMNA | |
| SCHEMBL945083 | 0.82 | BCHE (0.56) | BCHEPTGS2ALOX15ALDH1A1LMNA | |
| SCHEMBL23398382 | 0.80 | BCHE (0.56) | BCHEPTGS2ALOX15ALDH1A1LMNA | |
| SCHEMBL23398749 | 0.79 | BCHE (0.54) | BCHEPTGS2ALOX15ALDH1A1LMNA | |
| SCHEMBL23401048 | 0.79 | BCHE (0.54) | BCHEPTGS2ALOX15ALDH1A1LMNA | |
| Ampyrone SCHEMBL11674586 | 0.76 | BCHE (1.00) | BCHEPTGS2ALOX15ALDH1A1LMNA | |
| Ampyrone SCHEMBL18159502 | 0.76 | BCHE (1.00) | BCHEPTGS2ALOX15ALDH1A1LMNA | |
| Ampyrone SCHEMBL128544 | 0.76 | BCHE (1.00) | BCHEPTGS2ALOX15ALDH1A1LMNA | |
| Ampyrone SCHEMBL1830291 | 0.74 | BCHE (0.96) | BCHEPTGS2ALOX15ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764082-B1 | 4-5-diamino-N,N-dihydro-pyrazol-3-one derivatives for use in composition for dyeing keratin fibres | OREAL (FR) | 2011-06-29 | — | — | EP | claimed |
| US-7642360-B2 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | L'OREAL S.A. (FR) | 2010-01-05 | — | — | US | claimed |
| US-20080071092-A1 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | L'OREAL S.A. | 2008-03-20 | — | — | US | claimed |
| US-7285137-B2 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | L'OREAL, S.A. (FR) | 2007-10-23 | — | — | US | claimed |
| EP-1764082-A2 | 4-5-diamino-N,N-dihydro-pyrazol-3-one derivatives for use in composition for dyeing keratin fibres | L'OREAL (FR) | 2007-03-21 | — | — | EP | claimed |
| US-20050166335-A1 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | L'OREAL S.A. (FR) | 2005-08-04 | — | — | US | claimed |
| EP-1550656-A1 | 4-5-diamino-n,n-dihydro-pyrazol-3-one derivatives for use in composition for dyeing keratin fibres | L'OREAL (FR) | 2005-07-06 | — | — | EP | claimed |
| US-10226411-B2 | Dyeing composition comprising a fatty substance, a non-ionic guar gum, an amphoteric surfactant and a non-ionic or anionic surfactant, and an oxidizing agent, dyeing process and suitable device | L'OREAL (FR) | 2019-03-12 | — | — | US | disclosed |
| US-10226411-B2 | Dyeing composition comprising a fatty substance, a non-ionic guar gum, an amphoteric surfactant and a non-ionic or anionic surfactant, and an oxidizing agent, dyeing process and suitable device | L'OREAL (FR) | 2019-03-12 | — | — | US | disclosed |
| US-10137063-B2 | Dye composition comprising nonionic guar gum or a nonionic derivative thereof, process and device for the same | L'OREAL (FR) | 2018-11-27 | — | — | US | disclosed |
| EP-2879651-B1 | DYE COMPOSITION COMPRISING NONIONIC GUAR GUM OR A NONIONIC DERIVATIVE THEREOF, PROCESS AND DEVICE FOR THE SAME | OREAL (FR) | 2018-09-19 | — | — | EP | disclosed |
| EP-2647409-B1 | Composition comprising a modified cellulose derivative, a fatty acid ester and oxidising dyes, dyeing method for oxidation and use | L'ORÉAL (FR) | 2017-10-04 | — | — | EP | disclosed |
| EP-2879650-B1 | DYEING COMPOSITION COMPRISING A FATTY SUBSTANCE, A NON-IONIC GUAR GUM, AN AMPHOTERIC SURFACTANT AND A NON-IONIC OR ANIONIC SURFACTANT, AND AN OXIDIZING AGENT, DYEING PROCESS AND SUITABLE DEVICE | OREAL (FR) | 2017-07-26 | — | — | EP | disclosed |
| US-20060277691-A1 | Composition for dyeing keratin fibers, comprising a diamino-N,N-dihydropyrazolone compound, a coupler, and a polyol | L'OREAL S.A. (FR) | 2006-12-14 | — | — | US | disclosed |
| US-20060277693-A1 | Composition for dyeing keratin fibers, comprising at least one diamino-N,N-dihydropyrazolone derivative, at least one coupler and at least one associative polyurethane polymer | L'OREAL S.A. (FR) | 2006-12-14 | — | — | US | disclosed |
| US-20060277692-A1 | Composition for dyeing keratin fibers, comprising at least one diamino-N,N-dihydropyrazolone derivative, at least one coupler, and at least one surfactant | L'OREAL S.A. (FR) | 2006-12-14 | — | — | US | disclosed |
| EP-1728499-A1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolone derivative and a 2,3-diaminopyridine coupler | L'OREAL (FR) | 2006-12-06 | — | — | EP | disclosed |
| EP-1728500-A1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolon derivative and a cationic oxidation dye | L'OREAL (FR) | 2006-12-06 | — | — | EP | disclosed |
| US-20050166335-A1 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | L'OREAL S.A. (FR) | 2005-08-04 | — | — | US | disclosed |
| EP-1550656-A1 | 4-5-diamino-n,n-dihydro-pyrazol-3-one derivatives for use in composition for dyeing keratin fibres | L'OREAL (FR) | 2005-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060277691-A1 | Composition for dyeing keratin fibers, comprising a diamino-N,N-dihydropyrazolone compound, a coupler, and a polyol | KRT18, C9, NDUFA10 | BCHE 4225/4885PTGS2 4120/4885ALOX15 3743/4885 |
| US-10226411-B2 | Dyeing composition comprising a fatty substance, a non-ionic guar gum, an amphoteric surfactant and a non-ionic or anionic surfactant, and an oxidizing agent, dyeing process and suitable device | KRT18, OAT, DSG1 | BCHE 2477/4885PTGS2 1172/4885ALOX15 403/4885 |
| US-20060277692-A1 | Composition for dyeing keratin fibers, comprising at least one diamino-N,N-dihydropyrazolone derivative, at least one coupler, and at least one surfactant | KRT18, DSP, DSG1 | BCHE 4665/4885PTGS2 3470/4885ALOX15 2941/4885 |
| US-20080071092-A1 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | KRT18, DAO, AOC1 | BCHE 4070/4885PTGS2 3947/4885ALOX15 2891/4885 |
| US-10137063-B2 | Dye composition comprising nonionic guar gum or a nonionic derivative thereof, process and device for the same | KRT18, OAT, SHH | BCHE 1746/4885PTGS2 1226/4885ALOX15 1040/4885 |
| US-20050166335-A1 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | KRT18, DAO, AOC1 | BCHE 4070/4885PTGS2 3947/4885ALOX15 2891/4885 |
| US-20060277693-A1 | Composition for dyeing keratin fibers, comprising at least one diamino-N,N-dihydropyrazolone derivative, at least one coupler and at least one associative polyurethane polymer | KRT18, PRKDC, DSP | BCHE 4408/4885PTGS2 3897/4885ALOX15 3732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.