SCHEMBL23401656

SCHEMBL23401656

CC(C)n1c(=O)c(N)c(-c2ccccc2)n1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.44
PTGS2 P35354 1/20 0.44
LMNA P02545 2/20 0.40
ADORA3 P0DMS8 1/20 0.40
KDM4E B2RXH2 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2D6 P10635 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
POLB P06746 1/20 0.35
CDK8 P49336 1/20 0.35
ACVR1 Q04771 1/20 0.35
PABPC1 P11940 1/20 0.35
CASP3 P42574 1/20 0.35
CASP7 P55210 1/20 0.35
CASP9 P55211 1/20 0.35
CASP6 P55212 1/20 0.35
EIF2AK3 Q9NZJ5 4/20 0.34
EIF2AK4 Q9P2K8 3/20 0.34
ALDH1A1 P00352 2/20 0.34
ALOX15 P16050 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23403162 0.81 BCHE (0.58) BCHEPTGS2LMNAADORA3KDM4E
SCHEMBL23402967 0.80 BCHE (0.51) BCHEPTGS2LMNAADORA3KDM4E
SCHEMBL23398382 0.79 BCHE (0.56) BCHEPTGS2LMNAADORA3KDM4E
SCHEMBL3694660 0.79 BCHE (0.65) BCHEPTGS2LMNAADORA3KDM4E
SCHEMBL23400776 0.78 BCHE (0.41) BCHEPTGS2LMNAADORA3KDM4E
SCHEMBL23401596 0.77 BCHE (0.43) BCHEPTGS2LMNAADORA3KDM4E
SCHEMBL23402591 0.77 PTGS2 (0.43) BCHEPTGS2LMNAADORA3KDM4E
SCHEMBL23403522 0.76 KDM4E (0.38) PTGS2LMNAADORA3KDM4ECYP1A2
SCHEMBL23400331 0.75 BCHE (0.44) BCHEPTGS2KDM4ECYP1A2SMN1; SMN2
SCHEMBL23402523 0.75 BCHE (0.51) BCHEPTGS2KDM4ECYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed